[HTML][HTML] Factors determining the specificity of signal transduction by guanine nucleotide-binding protein-coupled receptors. II. Preferential coupling of the alpha 2C …
I Coupry, E Duzic, SM Lanier - Journal of Biological Chemistry, 1992 - Elsevier
Cell to cell communication by many hormones and neurotransmitters involves three major
entities: receptor (R), G-protein (G), and effector molecule (E). Plasticity in this system is …
entities: receptor (R), G-protein (G), and effector molecule (E). Plasticity in this system is …
δ-opioid-receptor-mediated inhibition of adenylate cyclase is transduced specifically by the guanine-nucleotide-binding protein Gi2
FR McKenzie, G Milligan - Biochemical Journal, 1990 - portlandpress.com
Mouse neuroblastoma x rat glioma hybrid cells (NG108-15) express an opioid receptor of
the delta subclass which both stimulates high-affinity GTPase activity and inhibits adenylate …
the delta subclass which both stimulates high-affinity GTPase activity and inhibits adenylate …
Identification of lung major GTP-binding protein as Gi2 and its distribution in various rat tissues determined by immunoassay
T Asano, R Morishita, R Semba, H Itoh, Y Kaziro… - Biochemistry, 1989 - ACS Publications
Revised Manuscript Received February 16, 1989 abstract: Antisera were raised in rabbits
against the 40-kDa a subunit of bovine lung GTP-binding protein, which were identified as …
against the 40-kDa a subunit of bovine lung GTP-binding protein, which were identified as …
A Drosophila G-protein alpha subunit, Gf alpha, expressed in a spatially and temporally restricted pattern during Drosophila development.
F Quan, WJ Wolfgang, M Forte - Proceedings of the …, 1993 - National Acad Sciences
Heterotrimeric guanine nucleotide binding proteins (G proteins) couple receptors for
extracellular signals to intracellular second messenger-generating systems. Previous …
extracellular signals to intracellular second messenger-generating systems. Previous …
Analysis of receptor-stimulated and basal guanine nucleotide binding to membrane G proteins by sodium dodecyl sulfate-polyacrylamide gel electrophoresis
E Friedman, P Butkerait, HY Wang - Analytical biochemistry, 1993 - Elsevier
A method to study [α-32P] GTP binding to the α subunit of GTP-binding proteins in rat brain
membranes is described. This method measures receptor-stimulated GTP binding to …
membranes is described. This method measures receptor-stimulated GTP binding to …
Antibodies which recognize the C-terminus of the inhibitory guanine-nucleotide-binding protein (Gi) demonstrate that opioid peptides and foetal-calf serum stimulate …
FR McKenzie, ECH Kelly, CG Unson… - Biochemical …, 1988 - portlandpress.com
We investigated the mechanisms of receptor-mediated stimulation of high-affinity GTPase
activity in response to opioid peptides and to foetal-calf serum in membranes of the …
activity in response to opioid peptides and to foetal-calf serum in membranes of the …
Characterization of G-protein alpha subunits in the Gq class: expression in murine tissues and in stromal and hematopoietic cell lines.
TM Wilkie, PA Scherle… - Proceedings of the …, 1991 - National Acad Sciences
Murine G alpha 14 and G alpha 15 cDNAs encode distinct alpha subunits of heterotrimeric
guanine nucleotide-binding proteins (G proteins). These alpha subunits are related to …
guanine nucleotide-binding proteins (G proteins). These alpha subunits are related to …
[HTML][HTML] Molecular cloning of five GTP-binding protein cDNA species from rat olfactory neuroepithelium.
DT Jones, RR Reed - Journal of Biological Chemistry, 1987 - Elsevier
Biochemical studies in vertebrate olfactory tissue indicate that certain odorants stimulate
adenylyl cyclase in a GTP-dependent manner. Additionally, immunochemical and toxin …
adenylyl cyclase in a GTP-dependent manner. Additionally, immunochemical and toxin …
Differential tissue expression and developmental regulation of guanine nucleotide binding regulatory proteins and their messenger RNAs in rat heart.
CW Luetje, KM Tietje, JL Christian… - Journal of Biological …, 1988 - Elsevier
The expression and developmental regulation of the alpha and beta subunits of the guanine
nucleotide binding regulatory proteins, Gi and Go, were examined in rat atria and ventricles …
nucleotide binding regulatory proteins, Gi and Go, were examined in rat atria and ventricles …
[HTML][HTML] In vitro synthesis of G protein βγ dimers
CJ Schmidt, EJ Neer - Journal of Biological Chemistry, 1991 - Elsevier
The guanine nucleotide-binding proteins (G proteins), which play a central role in coupling
membrane-bound receptors to intracellular effectors, are heterotrimers composed of α, β …
membrane-bound receptors to intracellular effectors, are heterotrimers composed of α, β …