Microbial metabolite: a link between psychological stress and epithelial disturbance

D Reed - Gastroenterology, 2024 - Elsevier
A recent study by Wei, Liu, Hou et al the investigated how psychological stress conveys
epithelial disturbance. Using chronic restraint stress (CRS) to model psychological stress in …

[HTML][HTML] A Diet-Microbe-Epithelia Metabolic Trilogue in the Stressed Gut

H Hao, X Zheng - Microbiology, 2021 - communities.springernature.com
Gut epithelial integrity is dynamically shaped by microbial signals amenable to
environmental and psychological modulation. Here we dissect dietary impact on …

Exposure to a social stressor disrupts the community structure of the colonic mucosa-associated microbiota

JD Galley, MC Nelson, Z Yu, SE Dowd, J Walter… - BMC microbiology, 2014 - Springer
Background The microbiota of the mammalian gastrointestinal (GI) tract consists of diverse
populations of commensal bacteria that interact with host physiological function …

The structures of the colonic mucosa-associated and luminal microbial communities are distinct and differentially affected by a prolonged murine stressor

JD Galley, Z Yu, P Kumar, SE Dowd, M Lyte… - Gut …, 2014 - Taylor & Francis
The commensal microbiota of the human gastrointestinal tract live in a largely stable
community structure, assisting in host physiological and immunological functions. Changes …

Psychological stress disrupts intestinal epithelial cell function and mucosal integrity through microbe and host-directed processes

JM Allen, AR Mackos, RM Jaggers, PC Brewster… - bioRxiv, 2021 - biorxiv.org
Psychological stress alters the gut microbiota and predisposes individuals to increased risk
for enteric infections and chronic bowel conditions. Intestinal epithelial cells (IECs) are …

Chronic psychological stress disrupted the composition of the murine colonic microbiota and accelerated a murine model of inflammatory bowel disease

Y Watanabe, S Arase, N Nagaoka, M Kawai… - PloS one, 2016 - journals.plos.org
The effect of psychological stress on the gastrointestinal microbiota is widely recognized.
Chronic psychological stress may be associated with increased disease activity in …

Psychological stress disrupts intestinal epithelial cell function and mucosal integrity through microbe and host-directed processes

JM Allen, AR Mackos, RM Jaggers, PC Brewster… - Gut …, 2022 - Taylor & Francis
Psychological stress alters the gut microbiota and predisposes individuals to increased risk
for enteric infections and chronic bowel conditions. Intestinal epithelial cells (IECs) are …

Prolonged restraint stressor exposure in outbred CD-1 mice impacts microbiota, colonic inflammation, and short chain fatty acids

RM Maltz, J Keirsey, SC Kim, AR Mackos… - PloS one, 2018 - journals.plos.org
Stressor-exposure has been shown to exacerbate inflammation and change the composition
of the gastrointestinal microbiota; however stressor-induced effects on microbiota-derived …

IDDF2021-ABS-0074 Gut microbial metabolite of tryptophan retards intestinal stem cell maintenance under psychological stress in mice

X Zheng, Y Liu - 2021 - gut.bmj.com
Background Psychosocial stress has a negative impact on gastrointestinal homeostasis in
part via brain-gut microbiota mechanisms that are poorly understood. Despite the significant …

Stressor exposure has prolonged effects on colonic microbial community structure in Citrobacter rodentium-challenged mice

JD Galley, AR Mackos, VA Varaljay, MT Bailey - Scientific reports, 2017 - nature.com
Stressor exposure significantly affects the colonic mucosa-associated microbiota, and
exacerbates Citrobacter rodentium-induced inflammation, effects that can be attenuated with …