Sickle cell disease (SCD) is a group of complex genetic disorders with multisystem
manifestations. This statement provides pediatricians in primary care and subspecialty …

Sickle cell disease (SCD) is a group of complex genetic disorders with multisystem
manifestations. This statement provides pediatricians in primary care and subspecialty …

Purpose: To familiarize primary care providers (PCPs) with the pathophysiological
processes, diagnostic evaluation, and medical management of sickle hemoglobinopathies …

Sickle cell disease (SCD) is the name for a group of genetic blood disorders caused by
sickle hemoglobin (Hb S). The 2 key features of SCD are chronic hemolytic anemia and …

The first clinical description of sickle cell anemia was published in 1910 by Herri~ k?~ who
reported some of the clinical and hematologic manifestations of the disorder in a 20-year-old …

As more children are appropriately being diagnosed, the burden of sickle cell disease is
increasing greatly in Africa and in high-resource countries such as the United States and …

Thirty years ago, the first major federal legislation concerning sickle cell disease treatment
was passed, resulting in the development of comprehensive sickle cell centers. We are now …

OBJECTIVE: Sickle cell disease (SCD) affects 70 000 to 100 000 people in the United
States, and 2000 infants are born with the disease each year. The purpose of this study was …

Family physicians are the primary and sometimes only health care resource for families
affected by sickle cell disease. Recently published guidelines provide important …

Treatment advances over the past 25 years have significantly decreased morbidity and
mortality in children with sickle cell disease. Aggressive management of fever, early …