The roles of nitric oxide (NO) in the heart have been studied intensely ever since the first
report nearly 2 decades ago showing that endogenous NO modulates cardiac myocyte …

Endogenous myocardial nitric oxide (NO) may modulate the transition from adaptive to
maladaptive hypertrophy leading to heart failure. This review summarizes the information on …

The role of nitric oxide (NO) as a regulator of cardiac contraction was suggested in the early
nineties, but a consensual view of its main functions in cardiac physiology has only recently …

Nitric oxide synthases (NOSs) comprise a family of enzymes that generate the freely
diffusible, free radical gas NO, by the conversion of L-arginine to L-citrulline in the presence …

Recognition of significance of nitric oxide synthases (NOS) in cardiovascular regulations has
led to intensive research and development of therapies focused on NOS as potential …

There is now ample evidence for a regulatory role of nitric oxide (NO) in various aspects of
cardiac myocyte biology, with important resulting effects on heart function. After the initial …

Nitric oxide (NO) is generated by NO synthases (NOSs) that convert L-arginine to L-citrulline
in the presence of molecular oxygen, nicotinamide-adenine dinucleotide phosphate …

Nitric oxide (NO) is produced from virtually all cell types composing the myocardium and
regulates cardiac function through both vascular-dependent and-independent effects. The …

Nitric oxide (NO) has been shown to regulate cardiac function, both in physiological
conditions and in disease states. However, several aspects of NO signalling in the …

Nitric oxide (NO) has essential roles in heart physiology, including the regulation of
myocardial contractility and coronary blood flow, and in heart pathophysiology, particularly …