Circular RNAs: emerging regulators of the major signaling pathways involved in cancer progression

M Papatsirou, PI Artemaki, P Karousi, A Scorilas… - Cancers, 2021 - mdpi.com
Simple Summary Circular RNAs (circRNAs) are single-stranded RNA molecules that form a
covalently closed loop structure. They are characterized by distinct features and …

Circular RNAs modulate cancer hallmark and molecular pathways to support cancer progression and metastasis

AA Yarmishyn, AA Ishola, CY Chen, ND Verusingam… - Cancers, 2022 - mdpi.com
Simple Summary Circular RNAs (circRNA) are a type of RNA molecule of circular shape that
are now being extensively studied due to the important roles they play in different biological …

[HTML][HTML] Circular RNAs: emerging role in cancer diagnostics and therapeutics

A Rajappa, S Banerjee, V Sharma… - Frontiers in molecular …, 2020 - frontiersin.org
Circular RNAs (circRNAs) are rapidly coming to the fore as major regulators of gene
expression and cellular functions. They elicit their influence via a plethora of diverse …

[HTML][HTML] Circular RNAs in cancer: novel insights into origins, properties, functions and implications

J Li, J Yang, P Zhou, Y Le, C Zhou, S Wang… - American journal of …, 2015 - ncbi.nlm.nih.gov
Circular RNAs (circRNAs) are a large class of RNAs that, unlike linear RNAs, form covalently
closed continuous loops and have recently shown huge capabilities as gene regulators in …

Circular RNAs in cancer: opportunities and challenges in the field

LS Kristensen, TB Hansen, MT Venø, J Kjems - Oncogene, 2018 - nature.com
Circular RNA (circRNA) is a novel member of the noncoding cancer genome with distinct
properties and diverse cellular functions, which is being explored at a steadily increasing …

Circular RNAs in cancer

S Lux, L Bullinger - Circular RNAs: Biogenesis and Functions, 2018 - Springer
Circular RNAs (circRNAs) constitute a class of RNAs that only recently have come into the
focus of the scientific cancer community after it was revealed that they are very abundant …

Insights into the evolving roles of circular RNAs in cancer

KL Harper, TJ Mottram, A Whitehouse - Cancers, 2021 - mdpi.com
Simple Summary The central dogma of RNA biology was traditionally governed by the
transcription of DNA into messenger RNA (mRNA) followed by translation into protein. As …

CircRNA in cancer: fundamental mechanism and clinical potential

L Chen, G Shan - Cancer letters, 2021 - Elsevier
Abstract Circular RNAs (CircRNAs) are a class of single-stranded noncoding RNAs that are
formed in a circular conformation via non-canonical splicing or back-splicing events …

Circular RNAs: emerging cancer biomarkers and targets

Y Zhang, W Liang, P Zhang, J Chen, H Qian… - Journal of Experimental …, 2017 - Springer
CircRNAs are a class of RNA molecules that structurally form closed loops. CircRNAs are
abundant in eukaryotic transcripts and show certain levels of tissue and cell specificity …

Circular RNA: metabolism, functions and interactions with proteins

WY Zhou, ZR Cai, J Liu, DS Wang, HQ Ju, RH Xu - Molecular cancer, 2020 - Springer
Abstract Circular RNAs (CircRNAs) are single-stranded, covalently closed RNA molecules
that are ubiquitous across species ranging from viruses to mammals. Important advances …