Comprehensive landscape and future perspectives of circular RNAs in colorectal cancer

F Long, Z Lin, L Li, M Ma, Z Lu, L Jing, X Li, C Lin - Molecular cancer, 2021 - Springer
Colorectal cancer (CRC) is a common hereditary tumor that is often fatal. Its pathogenesis
involves multiple genes, including circular RNAs (circRNAs). Notably, circRNAs constitute a …

Circular RNAs serve as novel biomarkers and therapeutic targets in cancers

S Fang, J Pan, C Zhou, H Tian, J He… - Current Gene …, 2019 - ingentaconnect.com
Circular RNAs (circRNAs) are a class of non-coding RNAs (ncRNAs) that structurally form
closed loops without 5'-end cap and 3'-end poly (A) tail unlike linear RNAs. CircRNAs are …

[HTML][HTML] Circular RNA: a novel biomarker and therapeutic target for human cancers

B Lei, Z Tian, W Fan, B Ni - International journal of medical …, 2019 - ncbi.nlm.nih.gov
Circular (circ) RNAs, a newly recognized class of noncoding RNA, have been implicated in
the occurrence and development of several diseases, including neurological and …

Circular RNAs in cancer: an emerging key player

Y Dong, D He, Z Peng, W Peng, W Shi, J Wang… - Journal of hematology & …, 2017 - Springer
Circular RNAs (circRNAs) are a class of endogendous RNAs that form a covalently closed
continuous loop and exist extensively in mammalian cells. Majority of circRNAs are …

[HTML][HTML] Circular RNAs as potential biomarkers for cancer diagnosis and therapy

F Wang, AJ Nazarali, S Ji - American journal of cancer research, 2016 - ncbi.nlm.nih.gov
Circular RNAs (circRNAs) are a naturally occurring type of universal and diverse
endogenous noncoding RNAs which unlike linear RNAs, have covalently linked ends. They …

Circular RNAs as biomarkers and therapeutic targets in cancer

A Beilerli, I Gareev, O Beylerli, G Yang, V Pavlov… - Seminars in cancer …, 2022 - Elsevier
Circular RNAs (circRNAs) are a class of single-stranded closed non-coding RNA molecules
(ncRNAs), which are formed as a result of reverse splicing of mRNAs. Despite their relative …

[HTML][HTML] A Circular RNAs: Emerging roles and new insights in human cancers

Z He, Q Zhu - Biomedicine & Pharmacotherapy, 2023 - Elsevier
Circular RNAs (circRNAs) are single-stranded, covalently closed RNA molecules formed by
mRNA exon back-splicing. Although the circRNA functions remain largely unknown, their …

Circular RNAs in the tumour microenvironment

Z Ma, Y Shuai, X Gao, X Wen, J Ji - Molecular Cancer, 2020 - Springer
Abstract Background Circular RNAs (circRNAs) are a new class of endogenous non-coding
RNAs (ncRNAs) widely expressed in eukaryotic cells. Mounting evidence has highlighted …

Circular RNA and its mechanisms in disease: from the bench to the clinic

B Han, J Chao, H Yao - Pharmacology & therapeutics, 2018 - Elsevier
The emerging recognition of the functional roles of circular RNAs (circRNAs) has given rise
to a new perspective regarding our understanding of cellular physiology and disease …

Deregulation of circular RNAs in cancer from the perspectives of aberrant biogenesis, transport and removal

Q Wu, P Li, M Wu, Q Liu - Frontiers in Genetics, 2019 - frontiersin.org
CircRNAs (circular RNAs) are a class of RNAs generated from circularization with multiple
novel functions. Recent studies have revealed the aberrant expression and aberrant …