Circular RNAs: characteristics, function and role in human cancer

S Chen, Y Zhao - 2018 - digitum.um.es
Circular RNAs (circRNAs) are universal and diverse endogenous noncoding RNAs
(ncRNAs) that are widely found in eukaryotic cells. They form a covalently closed …

Circular RNAs: biogenesis, function and role in human diseases

J Greene, AM Baird, L Brady, M Lim… - Frontiers in molecular …, 2017 - frontiersin.org
Circular RNAs (circRNAs) are currently classed as non-coding RNA (ncRNA) that, unlike
linear RNAs, form covalently closed continuous loops and act as gene regulators in …

Deregulation of circular RNAs in cancer from the perspectives of aberrant biogenesis, transport and removal

Q Wu, P Li, M Wu, Q Liu - Frontiers in Genetics, 2019 - frontiersin.org
CircRNAs (circular RNAs) are a class of RNAs generated from circularization with multiple
novel functions. Recent studies have revealed the aberrant expression and aberrant …

Circular RNAs in cancer–lessons learned from microRNAs

M Dragomir, GA Calin - Frontiers in oncology, 2018 - frontiersin.org
Circular RNAs (circRNA) are RNA molecules built from fragments of linear pre-messenger
RNAs and other linear RNA species through a process termed “back-splicing” in which the …

New insight into circRNAs: characterization, strategies, and biomedical applications

XY Feng, SX Zhu, KJ Pu, HJ Huang, YQ Chen… - … Hematology & Oncology, 2023 - Springer
Circular RNAs (circRNAs) are a class of covalently closed, endogenous ncRNAs. Most
circRNAs are derived from exonic or intronic sequences by precursor RNA back-splicing …

Circular RNAs function as ceRNAs to regulate and control human cancer progression

Y Zhong, Y Du, X Yang, Y Mo, C Fan, F Xiong, D Ren… - Molecular cancer, 2018 - Springer
Circular RNAs (circRNAs) are connected at the 3′ and 5′ ends by exon or intron
cyclization, forming a complete ring structure. circRNA is more stable and conservative than …

Role of circular RNAs in disease progression and diagnosis of cancers: An overview of recent advanced insights

SU Khan, MU Khan, MI Khan, AA Fadahunsi… - International journal of …, 2022 - Elsevier
Tumor microenvironment (TME) is a crucial regulator of tumor progression and cells in the
TME release a number of molecules that are responsible for anaplasticity, invasion …

[HTML][HTML] Circular RNAs: A novel type of biomarker and genetic tools in cancer

YN Han, SQ Xia, YY Zhang, JH Zheng, W Li - Oncotarget, 2017 - ncbi.nlm.nih.gov
Circular RNAs (circRNAs) are a novel type of universal and diverse endogenous noncoding
RNAs (ncRNAs) and they form a covalently closed continuous loop without 5′ or 3′ tails …

Circular RNAs regulate parental gene expression: A new direction for molecular oncology research

H Wang, X Gao, S Yu, W Wang, G Liu, X Jiang… - Frontiers in …, 2022 - frontiersin.org
CircRNAs have been the focus of research in recent years. They are differentially expressed
in various human tumors and can regulate oncogenes and tumor suppressor genes …

Novel insights into circular RNAs in clinical application of carcinomas

D Rong, W Tang, Z Li, J Zhou, J Shi… - OncoTargets and …, 2017 - Taylor & Francis
Circular RNAs (circRNAs), formed by nonsequential back-splicing of pre-messenger RNA
(pre-mRNA) transcripts, have been widely concerned in recent years. With advances in high …