Temporal development of autonomic dysfunction in heart failure: effects of age in an ovine rapid-pacing model

MA Horn, EF Bode, SJ Borland… - … Series A: Biomedical …, 2016 - academic.oup.com
Heart failure (HF) is predominantly a disease of older adults and characterized by extensive
sympatho-vagal imbalance leading to impaired reflex control of heart rate (HR). However …

Impacts of frailty on heart rate variability in aging mice: roles of the autonomic nervous system and sinoatrial node

TW Dorey, HJ Jansen, M Moghtadaei, KL Jamieson… - Heart rhythm, 2021 - Elsevier
Background Heart rate variability (HRV) is determined by intrinsic sinoatrial node (SAN)
activity and the autonomic nervous system (ANS). HRV is reduced in aging; however, aging …

[HTML][HTML] Integrative cardiovascular physiology and pathophysiology: rhythm dynamics of the aging heart: an experimental study using conscious, restrained mice

M Comelli, M Meo, DO Cervantes, E Pizzo… - American Journal of …, 2020 - ncbi.nlm.nih.gov
Heart rate variability (HRV) is a measure of variation in time interval between heartbeats and
reflects the influence of autonomic nervous system and circulating/locally released factors …

Early left ventricular dysfunction elicits activation of sympathetic drive and attenuation of parasympathetic tone in the paced canine model of congestive heart failure

GM Eaton, RJ Cody, E Nunziata, PF Binkley - Circulation, 1995 - Am Heart Assoc
Background Although autonomic imbalance is known to be characteristic of patients with
clinically overt symptomatic congestive heart failure, it is currently unknown whether this …

Age-related changes in cardiac autonomic modulation and heart rate variability in mice

C Piantoni, L Carnevali, D Molla, A Barbuti… - Frontiers in …, 2021 - frontiersin.org
Objective The aim of this study was to assess age-related changes in cardiac autonomic
modulation and heart rate variability (HRV) and their association with spontaneous and …

Rhythm dynamics of the aging heart: an experimental study using conscious, restrained mice

M Comelli, M Meo, DO Cervantes… - American Journal …, 2020 - journals.physiology.org
Heart rate variability (HRV) is a measure of variation in time interval between heartbeats and
reflects the influence of autonomic nervous system and circulating/locally released factors …

Heart rate variability in a progressive heart failure model with rapid ventricular pacing

C Ootaki, A Manzo, K Kamohara… - The heart surgery …, 2008 - journal.hsforum.com
Background: Heart rate variability (HRV) is an indicator of autonomic nervous system
functionality and a recognized predictor of cardiac death; however, the changes in HRV …

Respiratory-related heart rate variability in progressive experimental heart failure

S Motte, M Mathieu, S Brimioulle… - American Journal …, 2005 - journals.physiology.org
Heart failure is associated with autonomic imbalance, and this can be evaluated by a
spectral analysis of heart rate variability. However, the time course of low-frequency (LF) and …

Acclimation to a thermoneutral environment abolishes age-associated alterations in heart rate and heart rate variability in conscious, unrestrained mice

JE Axsom, AP Nanavati, CA Rutishauser, JE Bonin… - Geroscience, 2020 - Springer
Mice are among the most widely used translational models of cardiovascular aging and offer
a method to quickly assess lifespan changes in a controlled environment. The standard …

Heart failure duration progressively modulates the arrhythmia substrate through structural and electrical remodeling

VP Long III, IM Bonilla, P Vargas-Pinto, Y Nishijima… - Life sciences, 2015 - Elsevier
Aims Ventricular arrhythmias are a common cause of death in patients with heart failure
(HF). Structural and electrical abnormalities in the heart provide a substrate for such …