Strain-specific patterns of autonomic nervous system activity and heart failure susceptibility in mice

V Shusterman, I Usiene, C Harrigal… - American Journal …, 2002 - journals.physiology.org
Transgenic mice are widely used to study cardiac function, but strain-dependent differences
in autonomic nervous system activity (ANSA) have not been explored. We compared 1) short …

Age-related differences in cardiac autonomic control at resting state and in response to mental stress

B Grässler, M Dordevic, S Darius, L Vogelmann… - Diagnostics, 2021 - mdpi.com
Our goal was to investigate age-related differences in cardiac autonomic control by means
of heart rate variability (HRV). For this purpose, 30 healthy older and 34 younger adults were …

Canine nonischemic left ventricular dysfunction: a model of chronic human cardiomyopathy

Y Nishijima, DS Feldman, JD Bonagura… - Journal of cardiac …, 2005 - Elsevier
BACKGROUND: The mechanisms of cardiac remodeling during chronic heart failure remain
poorly defined. We sought to advance a chronic canine model of nonischemic …

Autonomic modulation and clinical outcome in patients with chronic heart failure

AF Folino, B Tokajuk, A Porta, S Romano… - International Journal of …, 2005 - Elsevier
OBJECTIVE: Several studies documented the relevance of autonomic activity in the
pathophysiology of heart failure. In our study we evaluated the adjustment of this activity …

Altered vagal and sympathetic control of heart rate in left ventricular dysfunction and heart failure

T Kinugawa, ME Dibner-Dunlap - American Journal of …, 1995 - journals.physiology.org
We investigated alterations in autonomic control of heart rate in conscious dogs with left
ventricular (LV) dysfunction in the presence and absence of heart failure (HF) due to rapid …

Regulation of cardiac autonomic nervous system control across frailty statuses: a systematic review

S Parvaneh, CL Howe, N Toosizadeh, B Honarvar… - Gerontology, 2015 - karger.com
Background: Frailty is a geriatric syndrome that leads to impairment in interrelated
physiological systems and progressive homeostatic dysregulation in physiological systems …

An ovine model of tachycardia-induced degenerative dilated cardiomyopathy and heart failure with prolonged onset

MJ Byrne, JS Raman, CA Alferness, MD Esler… - Journal of Cardiac …, 2002 - Elsevier
Background: The aim of this study was to develop a model of long-term progressive heart
failure (HF). Methods and Results: A cardiac output flowprobe was implanted on the …

[HTML][HTML] Telemetric long-term assessment of autonomic function in experimental heart failure

K Boden, P Pongratanakul, J Vogel… - … of Pharmacological and …, 2023 - Elsevier
Despite medical advances in the treatment of heart failure (HF), mortality remains high. It has
been shown that alterations of the autonomic-nervous-system (ANS) are associated with HF …

Food restriction alters the age-related decline in cardiac β-adrenergic responsiveness

GR Kelley, JT Herlihy - Mechanisms of ageing and development, 1998 - Elsevier
The responsiveness of the heart to β-adrenergic receptor stimulation declines with age. The
aim of this study was to determine whether food restriction (FR), the most effective means of …

Chronic vagus nerve stimulation improves autonomic control and attenuates systemic inflammation and heart failure progression in a canine high-rate pacing model

Y Zhang, ZB Popovic, S Bibevski, I Fakhry… - Circulation: Heart …, 2009 - Am Heart Assoc
Background—Autonomic dysfunction, characterized by sympathetic activation and vagal
withdrawal, contributes to the progression of heart failure (HF). Although the therapeutic …