Differential effects of aging on heart rate variability and blood pressure variability

L Fluckiger, JM Boivin, D Quilliot… - … Series A: Biomedical …, 1999 - academic.oup.com
Previous studies investigating autonomic cardiovascular control in elderly persons usually
included analysis of RR interval but not of blood pressure variability.“Physiological” blood …

Cardiac remodelling in a baboon model of intrauterine growth restriction mimics accelerated ageing

AH Kuo, C Li, J Li, HF Huber… - The Journal of …, 2017 - Wiley Online Library
Key points Rodent models of intrauterine growth restriction (IUGR) successfully identify
mechanisms that can lead to short‐term and long‐term detrimental cardiomyopathies but …

Impaired lusitropy-frequency in the aging mouse: role of Ca2+-handling proteins and effects of isoproterenol

CC Lim, R Liao, N Varma… - American Journal of …, 1999 - journals.physiology.org
We examined the relationship between age-associated lusitropic impairment, heart rate, and
Ca2+-handling proteins and assessed the efficacy of increasing left ventricular (LV) …

Ventricular electrophysiology in congestive heart failure and its correlation with heart rate variability and baroreflex sensitivity: a canine model study

SX Zhou, J Lei, C Fang, YL Zhang, JF Wang - Europace, 2009 - academic.oup.com
Aims This study investigated ventricular electrophysiological characteristics and the
correlation between these parameters and heart rate variability (HRV) and baroreflex …

Altered inotropic and lusitropic responses to heart rate in conscious dogs with tachycardia-induced heart failure

H Asanoi, S Ishizaka, S Joho, T Kameyama… - Journal of the American …, 1996 - Elsevier
Objectives. The effects of increasing heart rate on left ventricular contraction and relaxation
were examined in conscious dogs with tachycardia-induced heart failure under …

Heart rate variability reveals altered autonomic regulation in response to myocardial infarction in experimental animals

E Pizzo, S Berrettoni, R Kaul, DO Cervantes… - Frontiers in …, 2022 - frontiersin.org
The analysis of beating rate provides information on the modulatory action of the autonomic
nervous system on the heart, which mediates adjustments of cardiac function to meet …

Alterations in cardiac parasympathetic function in aged rats

AU Ferrari, A Daffonchio, S Gerosa… - American Journal of …, 1991 - journals.physiology.org
Aging impairs sympathetic and parasympathetic cardiac control. Although the reduced
sympathetic responses are known to depend on an age-related cardiac beta-adrenoceptor …

Changes in heart rate variability with age

M Reardon, M Malik - Pacing and clinical electrophysiology, 1996 - Wiley Online Library
Depressed heart rate variability (HRV) after a myocardial infarction is associated with
increased mortality. This is thought to be due to reduced parasympathetic activity and …

Autonomic nervous system activity imbalance in cardiomyopathic hamster

PL Giudice, JP Gagnol, A Bellucci… - Journal of …, 2000 - journals.lww.com
There is strong evidence that autonomic imbalance plays an important role in progression of
heart failure. Analysis of heart rate variability (HRV) has achieved substantial acceptance as …

Decreased maximal heart rate with aging is related to reduced β-adrenergic responsiveness but is largely explained by a reduction in intrinsic heart rate

DD Christou, DR Seals - Journal of applied physiology, 2008 - journals.physiology.org
A decrease in maximal exercise heart rate (HRmax) is a key contributor to reductions in
aerobic exercise capacity with aging. However, the mechanisms involved are incompletely …