Survanta, a clinically used bovine lung surfactant extract, in contact with surfactant in the
subphase, shows a coexistence of discrete monolayer islands of solid phase coexisting with …

To determine if lateral phase separation occurs in films of pulmonary surfactant, we used
epifluorescence microscopy and Brewster angle microscopy (BAM) to study spread films of …

Lung surfactant causes the surface tension, γ, in the alveoli to drop to nearly zero on
exhalation; in the upper airways γ is∼ 30 mN/m and constant. Hence, a surface tension …

The studies reported here used fluorescence microscopy and Brewster angle microscopy to
test the classical model of how pulmonary surfactant forms films that are metastable at high …

Pulmonary surfactant spreads on the thin (∼ 0.1μm) liquid layer that lines the alveoli,
forming a film that reduces surface tension and allows normal respiration. Pulmonary …

We have shown previously that lateral compression of pulmonary surfactant monolayers
initially induces separation of two phases but that these remix when the films become more …

Langmuir isotherms, fluorescence microscopy, and atomic force microscopy were used to
study lung surfactant specific proteins SP-B and SP-C in monolayers of …

The structures formed by a pulmonary surfactant model system of
dipalmitoylphosphatidylcholine (DPPC), dipalmitoylphosphatidylglycerol (DPPG), and …

Pulmonary surfactant functions by first flowing rapidly into the alveolar air/water interface, but
then resisting collapse from the surface when the adsorbed interfacial film is compressed …

Pulmonary surfactant maintains a putative surface-active film at the air-alveolar fluid
interface and prevents lung collapse at low volumes. Porcine lung surfactant extracts (LSE) …