Tocilizumab for patients with severe COVID-19: a retrospective, multi-center study

K Tomasiewicz, A Piekarska… - Expert Review of Anti …, 2021 - Taylor & Francis
Background Tocilizumab, an inhibitor of the interleukin-6 receptor, may decrease the
inflammatory response and control the symptoms of severe coronavirus disease 2019 …

Efficacy of tocilizumab in COVID‐19: a systematic review and meta‐analysis

M Aziz, H Haghbin, E Abu Sitta… - Journal of medical …, 2021 - Wiley Online Library
The efficacy of tocilizumab (TOC), monoclonal antibody against interleukin‐6 (IL‐6) receptor,
in patients with coronavirus disease‐2019 (COVID‐19) patients has led to conflicting results …

Tocilizumab for the treatment of adult patients with severe COVID‐19 pneumonia: a single‐center cohort study

M Fernández‐Ruiz, F López‐Medrano… - Journal of medical …, 2021 - Wiley Online Library
Abstract Coronavirus disease 2019 (COVID‐19) can lead to a massive cytokine release. The
use of the anti‐interleukin‐6 receptor monoclonal antibody tocilizumab (TCZ) has been …

Tocilizumab use in COVID‐19‐associated pneumonia

AK Okoh, E Bishburg, S Grinberg… - Journal of medical …, 2021 - Wiley Online Library
Background We sought to evaluate the effect of tocilizumab (TCB), a recombinant
humanized monoclonal antibody against soluble interleukin‐6 receptors, in patients …

Efficacy and safety of tocilizumab in hospitalized COVID-19 patients: a systematic review and meta-analysis

L Luo, T Luo, M Du, H Mei, Y Hu - Journal of Infection, 2022 - journalofinfection.com
Fowler et al. 1 proposed RNA RT-LAMP as a rapid and accurate tool to promptly identify
highly contagious individuals during the pandemic era. In the current vaccination era, it …

Off-label use of tocilizumab for the treatment of SARS-CoV-2 pneumonia in Milan, Italy

V Morena, L Milazzo, L Oreni, G Bestetti… - European journal of …, 2020 - Elsevier
Background Tocilizumab, a humanized monoclonal antibody, targets IL-6 receptors blocking
downstream pro-inflammatory effects of IL-6. In preliminary reports it was suggested to be …

Experience with tocilizumab in severe COVID-19 pneumonia after 80 days of follow-up: A retrospective cohort study

O Moreno-Pérez, M Andres, JM Leon-Ramirez… - Journal of …, 2020 - Elsevier
Objectives To describe the clinical characteristics and predictors of major outcomes in
patients treated with tocilizumab (TCZ) for severe COVID-19 pneumonia. Patients and …

Tocilizumab for treatment of mechanically ventilated patients with COVID-19

EC Somers, GA Eschenauer, JP Troost… - Clinical Infectious …, 2021 - academic.oup.com
Background Severe coronavirus disease 2019 (COVID-19) can manifest in rapid
decompensation and respiratory failure with elevated inflammatory markers, consistent with …

Factors predicting poor outcomes of patients treated with tocilizumab for COVID‑19‑associated pneumonia: A retrospective study

VE Georgakopoulou, D Basoulis… - Experimental and …, 2022 - spandidos-publications.com
The severe acute respiratory syndrome coronavirus‑2 (SARS‑CoV‑2) pandemic is a
significant global issue that has major implications for the healthcare system. The mortality …

Tocilizumab in critically ill COVID-19 patients: An observational study

MZ Mushtaq, SBZ Mahmood, A Almas, SA Wasti… - International …, 2022 - Elsevier
Tocilizumab decreases inflammatory response in the cytokine storm which is one of the
mechanisms behind the development of ARDS in COVID-19 patients. The objective of our …