Near-infrared spectroscopy (NIRS) is an emerging technique for continuous, noninvasive
bedside monitoring of tissue structure, oxygenation, and blood flow. It relies upon the …

Conventional brain imaging modalities are limited in that they image only secondary
physical manifestations of brain injury, which may occur well after the actual insult to the …

Near-infrared (IR) light easily penetrates biological tissue, and the information offered by in
vivo spectroscopy of cerebral oxygenation is detailed and comes with a high temporal …

The possibility to non-invasively image hypoxic tissue volumes based upon oxyand deoxy-
hemoglobin absorbance exists with the development of near-infrared (NIR) biomedical …

Advances in the ability to produce and process near-infrared (NIR) light for in vivo analysis
has led to an explosion in the number of techniques holding promise in the early detection …

Although near‐infrared spectroscopy (NIRS) was developed as a tool for clinical monitoring
of tissue oxygenation, it also has potential for neuroimaging. A wide range of different NIRS …

Near-infrared spectroscopy (NIRS) is widely used to measure cerebral oxygenation and
hemodynamics caused by brain activation. Blood volume and oxygenation are indicated by …

The ability to measure changes in tissue oxygenation noninvasively is of potential benefit to
managing a variety of problems in clinical medicine. One useful way to assess tissue …

Considerable progress has been made since 1977 when Frans Jobsis first described the
use of near infrared spectroscopy (NIRS) for tissue oxygenation monitoring. The early work …

Diffuse optical tomography (DOT) using near infrared (NIR) light has become a promising
modality because it has the capability to non-invasively quantify oxygen saturation and …