Molecular characterization of circulating tumor cells in breast cancer by a liquid bead array hybridization assay

A Markou, A Strati, N Malamos, V Georgoulias… - Clinical …, 2011 - academic.oup.com
BACKGROUND Molecular characterization of circulating tumor cells (CTCs) is crucial to
identify novel diagnostic and therapeutic targets for individualized therapies. We developed …

Gene expression profile of circulating tumor cells in breast cancer by RT-qPCR

A Strati, A Markou, C Parisi, E Politaki, D Mavroudis… - BMC cancer, 2011 - Springer
Abstract Background Circulating tumor cells (CTCs) have been associated with prognosis
especially in breast cancer and have been proposed as a liquid biopsy for repeated follow …

Molecular characterization of circulating tumor cells in large quantities of contaminating leukocytes by a multiplex real-time PCR

AM Sieuwerts, J Kraan, J Bolt-de Vries… - Breast cancer research …, 2009 - Springer
Detection of circulating tumor cells (CTCs) in whole blood from metastatic cancer patients by
the CellSearch™ CTC Test (Veridex LLC, Warren, NJ, USA) has been shown to have …

Detection and characterization of circulating tumor associated cells in metastatic breast cancer

Z Mu, N Benali-Furet, G Uzan, A Znaty, Z Ye… - International journal of …, 2016 - mdpi.com
The availability of blood-based diagnostic testing using a non-invasive technique holds
promise for real-time monitoring of disease progression and treatment selection. Circulating …

Single cell profiling of circulating tumor cells: transcriptional heterogeneity and diversity from breast cancer cell lines

AA Powell, AAH Talasaz, H Zhang, MA Coram… - PloS one, 2012 - journals.plos.org
Background To improve cancer therapy, it is critical to target metastasizing cells. Circulating
tumor cells (CTCs) are rare cells found in the blood of patients with solid tumors and may …

mRNA and microRNA expression profiles in circulating tumor cells and primary tumors of metastatic breast cancer patients

AM Sieuwerts, B Mostert, J Bolt-de Vries, D Peeters… - Clinical Cancer …, 2011 - AACR
Purpose: Molecular characterization of circulating tumor cells (CTC) holds great promise.
Unfortunately, routinely isolated CTC fractions currently still contain contaminating …

Comparison of three molecular assays for the detection and molecular characterization of circulating tumor cells in breast cancer

A Strati, S Kasimir-Bauer, A Markou, C Parisi… - Breast Cancer …, 2013 - Springer
Introduction Comparison studies between different analytical methodologies for circulating
tumor cells (CTC) detection and molecular characterization are urgently needed, since …

Gene expression profiling of circulating tumor cells and peripheral blood mononuclear cells from breast cancer patients

M Hensler, I Vančurová, E Becht, O Palata… - …, 2016 - Taylor & Francis
Circulating tumor cells (CTCs) are cancer cells that are released from a tumor into the
bloodstream. The presence of CTCs in peripheral blood has been associated with …

Circulating tumor cells in breast cancer: detection systems, molecular characterization, and future challenges

ES Lianidou, A Markou - Clinical chemistry, 2011 - academic.oup.com
BACKGROUND Circulating tumor cell (CTC) analysis is a promising new diagnostic field for
estimating the risk for metastatic relapse and metastatic progression in patients with cancer …

[HTML][HTML] A rapid nested polymerase chain reaction method to detect circulating cancer cells in breast cancer patients using multiple marker genes

LEI Liu, C Ma, Q Xu, L Cheng, L Xiao… - Oncology …, 2014 - spandidos-publications.com
The aim of the present study was to develop a simple and rapid method for the detection of
circulating cancer cells using multiple tumor markers and to investigate the clinical …