Calcium oxalate stone disease is the most common human urinary stone disease in the
Western Hemisphere. To understand different aspects of the disease, calcium oxalate …

Calcium oxalate nephrolithiasis in rats requires induction of hyperoxaluria which results in
increased urinary calcium oxalate supersaturation. As a result of low to mild chronic …

Calcium oxalate (CaOx) urolithiasis in rats is induced by producing hyperoxaluria.
Depending on the degree and length of hyperoxaluria, CaOx crystals may either form in the …

Purpose: The availability of various transgenic and knockout mice provides an excellent
opportunity to better understand the pathophysiology of calcium oxalate stone disease …

Our own studies and those of others have shown that the incidence of calcium oxalate
stones and plaques is markedly increased by nephrotoxins. The possible role of oxalate as …

In a rat-model system, tubular crystal retention as a possible mechanism for the etiology of
nephrolithiasis in man, was studied by conventional transmission electron microscopy. The …

Crystallization of salts in the urine is a process common to many mammals including
humans. The crystals are either harmlessly excreted as crystalluria particles or are retained …

Background: Although nephrotoxic in high doses, ethylene glycol (EG) has been used with
ammonium chloride (NH4Cl) or vitamin D3 to study calcium oxalate stone formation in rat …

Calcium oxalate urolithiasis is very common in western societies. In recent years significant
progress has been made in identifying and quantitating physico-chemical processes …

1. The effect of hyperuricosuria, simulated by increasing the concentration of dissolved
urate, on the crystallization of calcium oxalate in human urine was examined. 2. Twenty …