NLRX1 alleviates lipopolysaccharide-induced apoptosis and inflammation in chondrocytes by suppressing the activation of NF-κB signaling
D Ma, Y Zhao, J She, Y Zhu, Y Zhao, L Liu… - International …, 2019 - Elsevier
Osteoarthritis (OA) is a chronic debilitating disease characterized by joint degeneration.
Excessive chondrocyte apoptosis and inflammation contributes to articular cartilage …
Excessive chondrocyte apoptosis and inflammation contributes to articular cartilage …
[HTML][HTML] NLRC5 attenuates inflammatory response in IL-1β-stimulated human osteoarthritis chondrocytes through the NF-κB signaling pathway
Y Mu, Y Zhang, J Wu, Q Li - Aging (Albany NY), 2021 - ncbi.nlm.nih.gov
NOD-like receptor family caspase recruitment domain family domain containing 5 (NLRC5)
has been found to be a critical mediator of inflammatory response. However, the role of …
has been found to be a critical mediator of inflammatory response. However, the role of …
[HTML][HTML] Knockdown of LMX1B Suppressed Cell Apoptosis and Inflammatory Response in IL-1β-Induced Human Osteoarthritis Chondrocytes through NF-κB and …
Y Mu, L Wang, L Fu, Q Li - Mediators of Inflammation, 2022 - hindawi.com
Osteoarthritis (OA), a chronic degenerative joint disease, always occurred in the aging
population. There is evidence suggests that chondrocytes' survival, inflammation, and …
population. There is evidence suggests that chondrocytes' survival, inflammation, and …
[HTML][HTML] lncRNA‑NR024118 overexpression reverses LPS‑induced inflammatory injury and apoptosis via NF‑κB/Nrf2 signaling in ATDC5 chondrocytes
X Mei, J Tong, W Zhu, Y Zhu - Molecular Medicine …, 2019 - spandidos-publications.com
Osteoarthritis (OA) is one of the most prevalent types of chronic joint diseases. Chondrocytes
survival is closely associated with the destruction of joints in patients with OA. Long …
survival is closely associated with the destruction of joints in patients with OA. Long …
[HTML][HTML] Lentivirus-induced knockdown of LRP1 induces osteoarthritic-like effects and increases susceptibility to apoptosis in chondrocytes via the nuclear factor-κB …
E Yang, H Zheng, H Peng… - Experimental and …, 2015 - spandidos-publications.com
Low-density lipoprotein receptor-related protein 1 (LRP1) is known to regulate cell survival
and inflammation. The present study investigated the involvement of LRP1 in the regulation …
and inflammation. The present study investigated the involvement of LRP1 in the regulation …
NLRC5 promotes cell proliferation via regulating the NF-κB signaling pathway in Rheumatoid arthritis
Y Liu, X Yan, H Yu, Y Yao, J Wang, X Li, R Chen… - Molecular …, 2017 - Elsevier
Rheumatoid arthritis (RA) is a chronic autoimmune inflammatory disease and the
pathogenesis remains unclear. Previous studies suggested that fibroblast-like synoviocytes …
pathogenesis remains unclear. Previous studies suggested that fibroblast-like synoviocytes …
CY-09 attenuates the progression of osteoarthritis via inhibiting NLRP3 inflammasome-mediated pyroptosis
Y Zhang, Z Lin, D Chen, Y He - Biochemical and Biophysical Research …, 2021 - Elsevier
Excessive activation of inflammation in chondrocyte has been considered to be a major
reason cause of cellular death and degeneration in osteoarthritis (OA) development. The …
reason cause of cellular death and degeneration in osteoarthritis (OA) development. The …
[HTML][HTML] NF-κB signaling pathways in osteoarthritic cartilage destruction
MC Choi, J Jo, J Park, HK Kang, Y Park - Cells, 2019 - mdpi.com
Osteoarthritis (OA) is a type of joint disease associated with wear and tear, inflammation,
and aging. Mechanical stress along with synovial inflammation promotes the degradation of …
and aging. Mechanical stress along with synovial inflammation promotes the degradation of …
NLRP12 reduces proliferation and inflammation of rheumatoid arthritis fibroblast-like synoviocytes by regulating the NF-κB and MAPK pathways
X Zhang, H Nan, J Guo, J Liu - European Cytokine Network, 2021 - Springer
Rheumatoid arthritis (RA) is a chronic systemic autoimmune disease characterized by
abnormal synovial hyperplasia and the release of inflammatory cytokines. NLRP12 is a …
abnormal synovial hyperplasia and the release of inflammatory cytokines. NLRP12 is a …
Activating Nrf2 signalling alleviates osteoarthritis development by inhibiting inflammasome activation
Z Yan, W Qi, J Zhan, Z Lin, J Lin, X Xue… - Journal of Cellular …, 2020 - Wiley Online Library
Osteoarthritis (OA), which is characterized by proliferation of subchondral bone and the
degeneration of articular cartilage, is the most prevalent human arthritis. Nod‐like receptor …
degeneration of articular cartilage, is the most prevalent human arthritis. Nod‐like receptor …