Traumatic and nontraumatic brain injury results from severe disruptions in the cellular
microenvironment leading to massive loss of neuronal populations and increased …

Introduction Inflammatory cytokines play a key role in the pathogenesis of joint diseases
such as rheumatoid arthritis (RA). Current therapies target mainly tumor necrosis factor α …

Osteoarthritis (OA) is one of the most common degenerative disease in elderly patients
worldwide. Numerous microRNAs (miRs) have been reported to serve an important role in …

Nod-like receptors (NLRs) are intracellular sentinel proteins that are implicated in the
detection of microbes and danger signals, thereby controlling several key innate immune …

The metabolic syndrome could be induced by high fat diet, leading to cardiovascular
diseases, such as myocardial damage. Inflammation response and oxidative stress have …

Simple Summary Acute kidney injury is a common and severe group of clinical syndromes
with numerous causes, including sepsis. The molecular mechanisms underlying sepsis …

Abstract Objective Pattern‐recognition receptors (PRRs), such as Toll‐like receptors (TLRs)
and nucleotide‐binding oligomerization domain–containing protein 2 (NOD‐2), have been …

Abstract Objective Long noncoding RNAs (lncRNAs) regulate the occurrence and
development of osteoarthritis (OA), whereas the biological roles and mechanisms of the …

Background/Aims: Osteoarthritis (OA) is the most frequently occurring joint disease and
characterized by degeneration of cartilage. As the unique cell type in cartilage, chondrocytes …

Pyroptosis is triggered by inflammasomes after its activation by various inflammatory
stimulations, including lipopolysaccharide (LPS) and improper pH. This may result in …