Osteoarthritis (OA) is a common articular disease manifested by the destruction of cartilage
and compromised chondrogenesis in the aging population, with chronic inflammation of …

Diabetes is an independent risk factor for knee osteoarthritis (OA), and hyperglycaemia-
induced inflammation is considered to play an important role in their connection. The Toll …

Ligustilide (LIG) is the main lipophilic component of the Umbelliferae family of
pharmaceutical plants, including Radix angelicae sinensis and Ligusticum chuanxiong. LIG …

The etiology of osteoarthritis (OA) has been discussed widely, but the molecular
mechanisms beneath OA aggravation have not yet been investigated in detail. This study …

Osteoarthritis (OA) is a multifactorial and inflammatory disease characterized by cartilage
destruction that can cause disability among aging patients. There is currently no effective …

Osteoarthritis (OA), also known as degenerative joint disease or degenerative arthritis, is
characterized by chondrocyte apoptosis. The aim of the present study was to investigate the …

Background As dysregulation of immunometabolism plays a key role in the immunological
diseases, dyslipidemia frequently observed in rheumatoid arthritis (RA) patients (60%) is …

Receptor activator of nuclear factor-κB ligand (RANKL), a member of the Tumor Necrosis
Factor (TNF) superfamily, constitutes the master regulator of osteoclast formation and bone …

Osteoarthritis (OA) is a degenerative or posttraumatic condition of the joints. In OA
chondrocytes, Nrf2 functions as a stress response regulator with antioxidant and anti …

Acute lung injury is an acute inflammatory disease with high morbidity rate and high
mortality rate. However, there is still no effective clinical treatment to date. Our previous …