Therapeutic targets in alcohol-associated liver disease: progress and challenges

AD Adekunle, A Adejumo… - Therapeutic Advances in …, 2023 - journals.sagepub.com
Alcohol-associated liver disease (ALD) is a complex disease with rapidly increasing
prevalence. Although there are promising therapeutic targets on the horizon, none of the …

Alcohol-Associated Liver Disease: Evolving Concepts and Treatments

DS Prince, E Nash, K Liu - Drugs, 2023 - Springer
Alcohol is a prominent cause of liver disease worldwide with higher prevalence in
developed nations. The spectrum of alcohol-associated liver disease (ALD) encompasses a …

[PDF][PDF] A Call to Standardize Definitions, Data Collection, and Outcome Assessment to Improve Care in Alcohol‐Related Liver Disease

NT Shen, A Salajegheh, RS Brown Jr - Hepatology, 2019 - Wiley Online Library
Alcohol‐related liver disease (ALD) is highly prevalent and appears to be increasingly
reported with worsening mortality; thus, optimizing care in this patient population is …

Therapeutic pipeline in alcohol-associated liver disease

N Thakral, S Deutsch-Link… - Seminars in Liver …, 2023 - thieme-connect.com
Alcohol-associated liver disease is a leading cause of mortality and morbidity worldwide.
Patients with alcohol-associated liver disease are often diagnosed at advanced stage and …

[HTML][HTML] Pathophysiology and management of alcoholic liver disease: update 2016

F Stickel, C Datz, J Hampe, R Bataller - Gut and liver, 2017 - ncbi.nlm.nih.gov
Alcoholic liver disease (ALD) is a leading cause of cirrhosis, liver cancer, and acute and
chronic liver failure and as such causes significant morbidity and mortality. While alcohol …

[HTML][HTML] Diagnosis and management of alcoholic liver disease

M Dugum, A McCullough - Journal of clinical and translational …, 2015 - ncbi.nlm.nih.gov
Alcohol is a leading cause of liver disease and is associated with significant morbidity and
mortality. Several factors, including the amount and duration of alcohol consumption, affect …

[HTML][HTML] Alcohol-related liver disease: A global perspective

GEC Narro, LA Díaz, EK Ortega, MFB Garín… - Annals of …, 2024 - Elsevier
Alcohol-associated liver disease (ALD) represents one of the deadliest yet preventable
consequences of excessive alcohol use. It represents 5.1% of the global burden of disease …

Recent updates on alcoholic hepatitis

LC Shipley, S Kodali, AK Singal - Digestive and Liver Disease, 2019 - Elsevier
Alcoholic hepatitis (AH) is a unique clinical syndrome that affects patients with chronic and
active harmful alcohol consumption, and is associated with a high mortality of up to 40% at 1 …

[HTML][HTML] Alcoholic liver disease: pathogenesis and current management

NA Osna, TM Donohue Jr… - Alcohol research: current …, 2017 - ncbi.nlm.nih.gov
Excessive alcohol consumption is a global healthcare problem. The liver sustains the
greatest degree of tissue injury by heavy drinking because it is the primary site of ethanol …

Management of alcohol-related liver disease and its complications

J Cabezas - Clinical Drug Investigation, 2022 - Springer
Alcohol-related liver disease (ALD) is a major healthcare/economic burden and one of the
leading causes of liver transplantation. New epidemiological studies that detail the course of …