Staphylococcus Aureus Membrane Vesicles Kill Tumor Cells Through a Caspase-1-Dependent Pyroptosis Pathway

M Li, Y Wang, H Liu, X Huang, H Peng… - International Journal …, 2024 - Taylor & Francis
Introduction Nanosized outer membrane vesicles (OMVs) from Gram-negative bacteria have
attracted increasing interest because of their antitumor activity. However, the antitumor …

Staphylococcus aureus extracellular vesicles induce apoptosis and restrain mitophagy-mediated degradation of damaged mitochondria

X Wang, H Li, J Wang, H Xu, K Xue, X Liu… - Microbiological …, 2023 - Elsevier
Extracellular vesicles (EVs) are nano-sized bilayer EVs with various components. EV
secretion in pathogenic Gram-positive bacteria is a universal feature that can cause disease …

Capecitabine-loaded bacterial membrane vesicles derived from Enterococcus faecalis promotes apoptosis in HT-29 colon cancer cells

KE Gover, M Isik, D Barut, CT Sengel-Turk… - Biochemical …, 2022 - Elsevier
Bacterial membrane vesicles have recently attracted attention as drug delivery systems for
antineoplastic agents to target cancerous cells and reduce the side effects of free cytostatic …

[HTML][HTML] Methicillin-Resistant Staphylococcus aureus Membrane Vesicles Inhibit the Proliferation and Induce the Apoptosis of Epithelial Cells

X Chen, J Zhang, M Yang, G Du, F Chen - Pathogens, 2022 - mdpi.com
Staphylococcus aureus, or methicillin-resistant Staphylococcus aureus (MRSA), is the
predominant pathogen in skin and soft tissue infections (SSTIs), and MRSA membrane …

[HTML][HTML] The inhibition effects of Lentilactobacillus buchneri-derived membrane vesicles on AGS and HT-29 cancer cells by inducing cell apoptosis

A Abedi, F Tafvizi, P Jafari, N Akbari - Scientific Reports, 2024 - nature.com
In recent years, probiotics and their derivatives have been recognized as important
therapeutic agents in the fight against cancer. Therefore, this study aimed to investigate the …

Colorectal cancer-derived extracellular vesicles containing HSP70 enhance macrophage phagocytosis by up-regulating MARCO expression

Y Sun, W Xiao, Y Yu, Y Jiang, Z Xiao, D Huang… - Experimental Cell …, 2023 - Elsevier
In recent years, we have realized that extracellular vesicles (EVs) play a critical role in
regulating the intercellular communication between tumor and immune cells in the tumor …

Antineoplastic activity of Salmonella Typhimurium outer membrane nanovesicles

RGO Aly, MIH El-Enbaawy, SS Abd El-Rahman… - Experimental cell …, 2021 - Elsevier
Nano-sized Gram-negative bacterial outer membrane vesicles possess unique structural
and immunostimulatory effects that could be exploited to regress tumors by alerting the host …

[HTML][HTML] Bacterial membrane vesicles as smart drug delivery and carrier systems: a new nanosystems tool for current anticancer and antimicrobial therapy

P Aytar Çelik, K Erdogan-Gover, D Barut, BM Enuh… - Pharmaceutics, 2023 - mdpi.com
Bacterial membrane vesicles (BMVs) are known to be critical communication tools in several
pathophysiological processes between bacteria and host cells. Given this situation, BMVs …

[HTML][HTML] Staphylococcus aureus Produces Membrane-Derived Vesicles That Induce Host Cell Death

M Gurung, DC Moon, CW Choi, JH Lee, YC Bae, J Kim… - PloS one, 2011 - journals.plos.org
Gram-negative bacteria produce outer membrane vesicles that play a role in the delivery of
virulence factors to host cells. However, little is known about the membrane-derived vesicles …

[HTML][HTML] Bacteria derived extracellular vesicles in the pathogenesis and treatment of gastrointestinal tumours

Y Ge, F Sun, B Zhao, F Kong, Z Li, X Kong - Frontiers in Oncology, 2023 - frontiersin.org
Extracellular vesicles are fundamentally significant in the communication between cells.
Outer Membrane Vesicles (OMVs) are a special kind of EVs produced by Gram-negative …