Deletion of CBFB in a patient with acute myelomonocytic leukemia (AML M4Eo) and inversion 16

N Egan, J O'Reilly, L Chipper, M Higgins… - Cancer genetics and …, 2004 - Elsevier
Acute myelomonocytic leukemia with bone marrow eosinophilia (AML M4Eo) is a subtype of
AML with distinct morphological features. Inversion (16)(p13. 1q22), t (16; 16)(p13. 1; q22) …

[HTML][HTML] Detection of minimal residual disease in acute myelomonocytic leukemia with abnormal marrow eosinophils by nested polymerase chain reaction with allele …

J Hέbert, JM Cayuela, MT Daniel, R Berger, F Sigaux - Blood, 1994 - Elsevier
Acute myelomonocytic leukemia with bone marrow eosinophilia (AML-M4Eo in the French-
American-British [FA8] classification) is frequently associated with pericentric inversion of …

Acute myeloid leukaemia (FAB AML‐M4Eo) with cryptic insertion of cbfb resulting in cbfb‐Myh11 fusion

N Douet‐Guilbert, A Chauveau… - Hematological …, 2017 - Wiley Online Library
Abstract Inv (16)(p13q22) and t (16; 16)(p13; q22) are cytogenetic hallmarks of acute
myelomonoblastic leukaemia, most of them associated with abnormal bone marrow …

Inversion and deletion of 16q22 defined by array CGH, FISH, and RT-PCR in a patient with AML

AJ Dawson, S Bal, B McTavish, M Tomiuk, I Schroedter… - Cancer Genetics, 2011 - Elsevier
Acute myelomonocytic leukemia with eosinophilia is commonly associated with pericentric
inversions of chromosome 16, involving the core binding factor beta gene (CBFB) on 16q22 …

Detection of a novel CBFB/MYH11 variant fusion transcript (K-type) showing partial insertion of exon 6 of CBFB gene using two commercially available multiplex RT …

TS Park, ST Lee, J Song, KA Lee, JH Lee, J Kim… - Cancer genetics and …, 2009 - Elsevier
We report on a 20-year-old man with acute myeloid leukemia (AML) showing a distinct novel
CBFB/MYH11 variant fusion transcript. Initial results of bone marrow, chromosome, and flow …

Deletion of the long arm of chromosome 7 in myelomonocytic leukemia with bone marrow eosinophilia

Y Davidovitz, R Zimlichman, E Rosner… - Cancer genetics and …, 1997 - Elsevier
We report a 62-year-old man with acute myelomonocytic leukemia with bone marrow
eosinophilia (M4Eo), and a deletion of the long arm of chromosome 7. The patient presented …

Clinical aspects of expression of inversion 16 chromosomal fusion transcript CBFB/MYH11 in acute myelogenous leukemia subtype M1 with abnormal bone marrow …

BP Monahan, JT Rector, PP Liu, JD Cotelingam… - Leukemia, 1996 - europepmc.org
The pericentric inversion of chromosome 16 (inv (16)(p12q22)) is a characteristic karyotypic
abnormality associated with acute myeloid leukemia, most commonly of the M4Eo subtype. It …

A novel variant three-way translocation of inversion 16 in a case of AML-M4eo following low dose methotrexate therapy

S Li, RJ Couzi, GH Thomas, AD Friedman… - Cancer genetics and …, 2001 - Elsevier
We report a case of acute myelomonocytic leukemia with eosinophilia (AML-M4eo) in a 65-
year-old man following low dose methotrexate treatment for pemphigus vulgaris …

Deletion of 3′-CBFB gene in association with an inversion (16)(p13q22) and a loss of the Y chromosome in a 2-year-old child with acute myelogenous leukemia-M4

JR Batanian, Y Huang, R Fallon - Cancer genetics and cytogenetics, 2000 - Elsevier
Inversion 16 (p13q22) is most commonly associated with acute myelomonocytic leukemia
with abnormal eosinophils (M4). In association with this inversion, a proximal deletion at the …

Molecular Analysis of a New Variant of the CBFβ-MYH11 Gene Fusion

J Stulberg, S Kamel-Reid, K Chun… - Leukemia & …, 2002 - Taylor & Francis
The inv (16)(p13q22) is observed in 16% of patients with acute myelogenous leukemia
(AML). It is classically found in the AML M4Eo subtype, which has distinctive morphological …