Identification of four CCCH zinc finger proteins in Xenopus, including a novel vertebrate protein with four zinc fingers and severely restricted expression
J De, WS Lai, JM Thorn, SM Goldsworthy, X Liu… - Gene, 1999 - Elsevier
Tristetraprolin (TTP), the prototype of a class of CCCH zinc finger proteins, is a
phosphoprotein that is rapidly and transiently induced by growth factors and serum in …
phosphoprotein that is rapidly and transiently induced by growth factors and serum in …
Interactions of CCCH zinc finger proteins with mRNA: binding of tristetraprolin-related zinc finger proteins to AU-rich elements and destabilization of mRNA
WS Lai, E Carballo, JM Thorn, EA Kennington… - Journal of Biological …, 2000 - ASBMB
Macrophages derived from tristetraprolin (TTP)-deficient mice exhibited increased tumor
necrosis factor α (TNFα) release as a consequence of increased stability of TNFα mRNA …
necrosis factor α (TNFα) release as a consequence of increased stability of TNFα mRNA …
Polymorphisms in the genes encoding members of the tristetraprolin family of human tandem CCCH zinc finger proteins.
PJ Blackshear, RS Phillips… - Progress in nucleic …, 2003 - europepmc.org
The three known mammalian CCCH tandem zinc finger proteins of the tristetraprolin (TTP)
class have recently been demonstrated to be mRNA-binding proteins. The prototype, TTP …
class have recently been demonstrated to be mRNA-binding proteins. The prototype, TTP …
Tandem CCCH zinc finger proteins in mRNA binding
PJ Blackshear, RS Phillips, WS Lai - … finger proteins: from atomic contact to …, 2005 - Springer
A small family of mammalian zinc finger proteins containing an unusual putative tandem zinc
finger motif was identified approximately 13 years ago. The tandem zinc finger domain was …
finger motif was identified approximately 13 years ago. The tandem zinc finger domain was …
Phosphorylation of Tristetraprolin, a Potential Zinc Finger Transcription Factor, by Mitogen Stimulation in Intact Cells and by Mitogen-activated Protein Kinase in Vitro∗
GA Taylor, MJ Thompson, WS Lai… - Journal of Biological …, 1995 - ASBMB
Tristetraprolin (TTP) is a potential transcription factor that contains three PPPPG repeats and
two putative CCCH zinc fingers. TTP is encoded by the early response gene Zfp-36, which is …
two putative CCCH zinc fingers. TTP is encoded by the early response gene Zfp-36, which is …
Mitogens stimulate the rapid nuclear to cytosolic translocation of tristetraprolin, a potential zinc-finger transcription factor.
GA Taylor, MJ Thompson, WS Lai… - Molecular …, 1996 - academic.oup.com
Tristetraprolin (TTP) is the prototype of a group of potential transcription factors that contain
two or more unusual CCCH zinc fingers. TTP is encoded by the immediate-early response …
two or more unusual CCCH zinc fingers. TTP is encoded by the immediate-early response …
Characteristics of the intron involvement in the mitogen-induced expression of Zfp-36
WS Lai, MJ Thompson, PJ Blackshear - Journal of Biological Chemistry, 1998 - ASBMB
Zfp-36, the gene encoding the putative zinc finger protein tristetraprolin (TTP), is rapidly
induced in fibroblasts by a variety of growth factors. Recent gene knockout experiments …
induced in fibroblasts by a variety of growth factors. Recent gene knockout experiments …
Members of the tristetraprolin family of tandem CCCH zinc finger proteins exhibit CRM1-dependent nucleocytoplasmic shuttling
RS Phillips, SBV Ramos, PJ Blackshear - Journal of Biological Chemistry, 2002 - ASBMB
Members of the tristetraprolin (TTP) family of CCCH tandem zinc finger proteins can bind
directly to certain types of AU-rich elements (AREs) in mRNA. Experiments in TTP-deficient …
directly to certain types of AU-rich elements (AREs) in mRNA. Experiments in TTP-deficient …
Promoter Analysis of Zfp-36 the Mitogen-inducible Gene Encoding the Zinc Finger Protein Tristetraprolin (∗)
WS Lai, MJ Thompson, GA Taylor, Y Liu… - Journal of Biological …, 1995 - ASBMB
The gene encoding the putative zinc finger protein tristetraprolin (TTP), Zfp-36 is rapidly
induced by a variety of mitogens and growth factors. We show here that 77 base pairs 5′ of …
induced by a variety of mitogens and growth factors. We show here that 77 base pairs 5′ of …
Chorioallantoic fusion defects and embryonic lethality resulting from disruption of Zfp36L1, a gene encoding a CCCH tandem zinc finger protein of the Tristetraprolin …
DJ Stumpo, NA Byrd, RS Phillips, S Ghosh… - … and cellular biology, 2004 - Am Soc Microbiol
The mouse gene Zfp36L1 encodes zinc finger protein 36-like 1 (Zfp36L1), a member of the
tristetraprolin (TTP) family of tandem CCCH finger proteins. TTP can bind to AU-rich …
tristetraprolin (TTP) family of tandem CCCH finger proteins. TTP can bind to AU-rich …