White matter hyperintensities associated with small vessel disease impair social cognition beside attention and memory

J Kynast, L Lampe, T Luck, S Frisch… - Journal of Cerebral …, 2018 - journals.sagepub.com
Age-related white matter hyperintensities (WMH) are a manifestation of white matter damage
seen on magnetic resonance imaging (MRI). They are related to vascular risk factors and …

White matter hyperintensities, cognitive impairment and dementia: an update

ND Prins, P Scheltens - Nature Reviews Neurology, 2015 - nature.com
White matter hyperintensities (WMHs) in the brain are the consequence of cerebral small
vessel disease, and can easily be detected on MRI. Over the past three decades, research …

Role of white matter hyperintensities and related risk factors in vascular cognitive impairment: a review

Y Chen, X Wang, L Guan, Y Wang - Biomolecules, 2021 - mdpi.com
White matter hyperintensities (WMHs) of presumed vascular origin are one of the imaging
markers of cerebral small-vessel disease, which is prevalent in older individuals and closely …

The effects of longitudinal white matter hyperintensity change on cognitive decline and cortical thinning over three years

SJ Kim, DK Lee, YK Jang, H Jang, SE Kim… - Journal of Clinical …, 2020 - mdpi.com
White matter hyperintensity (WMH) has been recognised as a surrogate marker of small
vessel disease and is associated with cognitive impairment. We investigated the dynamic …

Severe cerebral white matter hyperintensities predict severe cognitive decline in patients with cerebrovascular disease history

C Dufouil, O Godin, J Chalmers, O Coskun… - Stroke, 2009 - Am Heart Assoc
Background and Purpose—Cerebral white matter hyperintensities (WMHs) are believed to
be the consequence of small vessel disease, and it is uncertain whether their extent predicts …

[HTML][HTML] White matter integrity in small vessel disease is related to cognition

AM Tuladhar, AGW van Norden, KF de Laat… - NeuroImage: Clinical, 2015 - Elsevier
Cerebral small vessel disease, including white matter hyperintensities (WMH) and lacunes
of presumed vascular origin, is common in elderly people and is related to cognitive …

What are white matter hyperintensities made of? Relevance to vascular cognitive impairment

JM Wardlaw, MC Valdés Hernández… - Journal of the …, 2015 - Am Heart Assoc
White matter hyperintensities (WMH) of presumed vascular origin, also referred to as
leukoaraiosis, are a very common finding on brain magnetic resonance imaging (MRI) or …

Correlation between white matter hyperintensities related gray matter volume and cognition in cerebral small vessel disease

Y Wang, Y Yang, T Wang, S Nie, H Yin, J Liu - Journal of Stroke and …, 2020 - Elsevier
Abstract Background and Aim The relationship between severity of cerebral small vessel
disease, as defined by white matter hyperintensities classification, and gray matter volume of …

Cognitive deficits are associated with frontal and temporal lobe white matter lesions in middle-aged adults living in the community

D Bunce, KJ Anstey, N Cherbuin, R Burns… - PloS one, 2010 - journals.plos.org
Background The association between brain white matter lesions and cognitive impairment in
old age is well established. However, little is known about this association in midlife. As this …

[HTML][HTML] Painting by lesions: White matter hyperintensities disrupt functional networks and global cognition

RA Crockett, CL Hsu, E Dao, R Tam, JJ Eng, TC Handy… - Neuroimage, 2021 - Elsevier
White matter hyperintensities (WMH) are a prominent feature of cerebral small vessel
disease and are associated with cognitive impairment. These deficits in cognition may be …