From signalling to form: the coordination of neural tube patterning

TJR Frith, J Briscoe, GLM Boezio - 2023 - crick.figshare.com
The development of the vertebrate spinal cord involves the formation of the neural tube and
the generation of multiple distinct cell types. The process starts during gastrulation …

Differentiation of the vertebrate neural tube

M Bronner-Fraser, SE Fraser - Current opinion in cell biology, 1997 - Elsevier
The vertebrate nervous system arises through a series of inductive interactions, beginning
with the induction of the neural plate and the rostrocaudal patterning of the neural tube. The …

Stem cell-derived models of spinal neurulation

C Mirdass, M Catala, M Bocel… - Emerging Topics in …, 2023 - portlandpress.com
Neurulation is a critical step in early embryonic development, giving rise to the neural tube,
the primordium of the central nervous system in amniotes. Understanding this complex, multi …

Neural tube morphogenesis

R Spörle, K Schughart - Current opinion in genetics & development, 1997 - Elsevier
Many important findings in the past year have helped to identify multiple cellular interactions
and signals in vertebrates that govern induction of neuroectoderm, its patterning, neural tube …

The cellular dynamics of neural tube formation

M van der Spuy, JX Wang… - Biochemical Society …, 2023 - portlandpress.com
The vertebrate brain and spinal cord arise from a common precursor, the neural tube, which
forms very early during embryonic development. To shape the forming neural tube, changes …

Regulatory pathways linking progenitor patterning, cell fates and neurogenesis in the ventral neural tube

J Briscoe, BG Novitch - … of the Royal Society B: Biological …, 2008 - royalsocietypublishing.org
The assembly of neural circuits in the vertebrate central nervous system depends on the
organized generation of specific neuronal subtypes. Studies over recent years have begun …

Neurulation: coming to closure

JL Smith, GC Schoenwolf - Trends in neurosciences, 1997 - cell.com
Neurulation is a morphogenetic event par excellence. During this highly choreographed four-
dimensional process, a flat sheet of ectoderm is transformed into an elongated tubular …

[PDF][PDF] Single cell transcriptomics reveals spatial and temporal dynamics of gene expression in the developing mouse spinal cord

J Delile, T Rayon, M Melchionda, A Edwards… - …, 2019 - journals.biologists.com
The coordinated spatial and temporal regulation of gene expression in the vertebrate neural
tube determines the identity of neural progenitors and the function and physiology of the …

Development of the vertebrate central nervous system: formation of the neural tube

NDE Greene, AJ Copp - Prenatal Diagnosis: Published in …, 2009 - Wiley Online Library
The developmental process of neurulation involves a series of coordinated morphological
events, which result in conversion of the flat neural plate into the neural tube, the primordium …

Neural tube closure: cellular, molecular and biomechanical mechanisms

E Nikolopoulou, GL Galea, A Rolo… - …, 2017 - journals.biologists.com
Neural tube closure has been studied for many decades, across a range of vertebrates, as a
paradigm of embryonic morphogenesis. Neurulation is of particular interest in view of the …