Detection of glutamate in the human brain at 3 T using optimized constant time point resolved spectroscopy

D Mayer, DM Spielman - … in Medicine: An Official Journal of the …, 2005 - Wiley Online Library
Abstract A CT‐PRESS sequence was implemented on a 3‐T MR scanner and optimized for
the detection of the C4 resonance of glutamate. By simulating the sequence using the full …

Very short echo time improves the precision of glutamate detection at 3T in 1H magnetic resonance spectroscopy

SA Wijtenburg, J Knight‐Scott - Journal of Magnetic Resonance …, 2011 - Wiley Online Library
Purpose: To examine the precision of glutamate detection using a very short echo time (TE)
phase rotation STEAM (PR‐STEAM) sequence. Materials and Methods: Spectrosopic data …

Measurement of brain glutamate and glutamine by spectrally‐selective refocusing at 3 Tesla

C Choi, NJ Coupland, PP Bhardwaj… - … in Medicine: An …, 2006 - Wiley Online Library
A new single‐voxel proton NMR spectrally‐selective refocusing method for measuring
glutamate (Glu) and glutamine (Gln) in the human brain in vivo at 3T is reported. Triple …

Detection of brain glutamate and glutamine in spectroscopic images at 4.1 T

GF Mason, JW Pan, SL Ponder… - Magnetic resonance …, 1994 - Wiley Online Library
Brain glutamate and glutamine were detected in healthy human volunteers in spectroscopic
images with a nominal voxel size of 2.25 cm3 at an echo time of 15 ms. Due to the increased …

Localized 1H NMR spectra of glutamate in the human brain

DL Rothman, CC Hanstock, OAC Petroff… - Magnetic resonance …, 1992 - Wiley Online Library
Localized 1H NMR spectra at TE= 12 ms were obtained from cerebralcortex of human
subjects using ISIS with surface suppression. The 2.29‐ppm resonance was assigned to C4 …

Measurement of brain glutamate using TE‐averaged PRESS at 3T

R Hurd, N Sailasuta, R Srinivasan… - … in Medicine: An …, 2004 - Wiley Online Library
A method is introduced that provides improved in vivo spectroscopic measurements of
glutamate (Glu), glutamine (Gln), choline (Cho), creatine (Cre), N‐acetyl compounds (NAtot …

Detection of glutamate/glutamine resonances by 1H magnetic resonance spectroscopy at 0.5 tesla

RW Prost, L Mark, M Mewissen… - Magnetic resonance in …, 1997 - Wiley Online Library
Midfield proton magnetic resonance spectroscopy (MRS) provides a noninvasive method to
monitor glutamate and glutamine (Glx) levels in vivo. Experiments to detect the γ and β …

Simultaneous detection of resolved glutamate, glutamine, and γ-aminobutyric acid at 4 T

J Hu, S Yang, Y Xuan, Q Jiang, Y Yang… - Journal of magnetic …, 2007 - Elsevier
A new approach is introduced to simultaneously detect resolved glutamate (Glu), glutamine
(Gln), and γ-aminobutyric acid (GABA) using a standard STEAM localization pulse sequence …

T2 measurement and quantification of glutamate in human brain in vivo

C Choi, NJ Coupland, PP Bhardwaj… - … in Medicine: An …, 2006 - Wiley Online Library
The proton NMR transverse relaxation time T2 of glutamate (Glu) in human brain was
measured by means of spectrally selective refocusing at 3.0 T in vivo. An 81.4‐ms‐long dual …

An investigation of glutamate quantification with PRESS and MEGA‐PRESS

H Cheng, A Wang, S Newman, U Dydak - NMR in Biomedicine, 2021 - Wiley Online Library
Glutamate is an important neurotransmitter. Although many studies have measured
glutamate concentration in vivo using magnetic resonance spectroscopy (MRS), researchers …