Neural tube defects (NTDs) are common birth defects and contribute to life-long disabilities,
high medical care costs, and perinatal and child mortality. This review is a primer on …

This review article discusses the epidemiology, risk factors, prenatal screening, diagnosis,
prevention potentials, and epidemiologic impact of neural tube defects (NTDs). The average …

This review article combines four disparate observations about Neural Tube Defects (NTDs).
They are the worldwide decline in the birth incidence that began prior to prenatal diagnosis; …

The worldwide prevalence of neural tube defects (NTDs) has fallen noticeably during the
past 30 years, but the specific etiology and causative mechanism of NTDs remain unknown …

Background Folate-sensitive neural tube defects (NTDs) are an important, preventable
cause of morbidity and mortality worldwide. There is a need to describe the current global …

Neural tube defects (NTD) are major congenital malformations affecting births worldwide.
NTD are associated with life‐long disability, significant medical care costs, and child …

Background Periconceptional use of vitamin supplements containing folic acid reduces the
risk of a neural tube defect (NTD). In November 1998, food fortification with folic acid was …

Neural tube defects (NTDs) are serious malformations affecting approximately 1 per 1000
births, yet the mechanisms by which they arise are unknown. There have been consistent …

Abstract Background Neural tube defects (NTDs) are associated with high rates of neonatal
mortality and morbidity worldwide. The promotion of folic acid fortification and …

OBJECTIVE:: Severe neural tube defects (NTDs) tend to occur with disproportionate
frequency in areas of high prevalence. The objective of our study was to determine the birth …