Abstract Background Drug resistance mutations (DRMs) increasingly jeopardize paediatric
HIV programmes in sub-Saharan Africa. As individual monitoring of DRMs and viral loads …

Abstract Background In Africa a high percentage of HIV-infected children continue to
experience HIV treatment failure despite enormous progress. In Benin (West Africa), there …

Objective: To investigate the prevalence and determinants of virologic failure and acquired
drug resistance-associated mutations (DRMs) in HIV-infected children and adolescents in …

Background A survey of drug resistance-associated mutations (DRMs) was conducted in
2009 among 77 vertically HIV-infected children not treated by antiretroviral drugs, followed …

Background Pretreatment HIV drug resistance (PDR) can impair virological response to
ART, jeopardizing effective treatment for children. Methods Children aged≤ 12 years …

Background: Limited data exist on drug resistance and antiretroviral treatment (ART)
outcomes in HIV-1–infected children in West Africa. We determined the prevalence of …

HIV-infected children are at high risk of acquiring drug-resistant viruses, which is of
particular concern in settings where antiretroviral drug options are limited. We aimed to …

Introduction HIV‐1 resistance data to inform treatment sequencing are limited for children
with virological failure on first‐and second‐line antiretroviral therapy (ART) in Sub‐Saharan …

A large cohort of 220 HIV-1-infected children (median [range] age: 12 [4–17] years) was
cared and followed up in the Central African Republic, including 198 in 1st-line and 22 in …

The rates of virological failure (VF) and HIV-1 drug resistance were evaluated in a cross-
sectional study in HIV-1-infected children living in Dakar, and taking antiretroviral treatment …