Major advances have been achieved in the treatment of osteosarcoma with the discovery of
several chemotherapeutic agents that were active in the disease. These agents comprise …

Over the last 30 years, the prognosis for children and young adults with osteosarcoma has
changed dramatically. Whereas once fewer than 20% of patients were cured by surgery …

OSTEOSARCOMA IS the most common primary bone malignancy affecting children and
young adults. Their outlook, compared with the results of treatment available 25 years ago …

Osteosarcoma is the bone tumor that most commonly affects children, adolescents, and
young adults. Before 1970, treatment primarily included surgical resection. However, the …

Osteosarcoma is the most common primary bone tumor in childhood and adolescence. The
use of combination chemotherapy and surgery enables long-term survival in approximately …

Osteosarcoma, the most common bone sarcoma, affects approximately 560 children and
adolescents annually in the United States. The incidence of new diagnoses peaks in the …

Pediatric and Adolescent Osteosarcoma provides a historical review of the nature of
osteosarcoma and the conflict that accompanied the introduction of adjuvant therapy for …

Abstract Learning Objectives After completing this course, the reader will be able to: Discuss
etiologic and biologic factors in osteosarcoma. Select the appropriate diagnostic work-up for …

The successful treatment of patients with osteosarcoma requires close cooperation within an
experienced multidisciplinary team including pediatric or medical oncologists, surgeons …

Osteosarcoma (OS) is the most common non-hematologic malignant tumor of bone in adults
and children. As sarcomas are more common in adolescents and young adults than most …