Genetic architecture of complex traits and accuracy of genomic prediction: coat colour, milk-fat percentage, and type in Holstein cattle as contrasting model traits

BJ Hayes, J Pryce, AJ Chamberlain, PJ Bowman… - PLoS …, 2010 - journals.plos.org
Prediction of genetic merit using dense SNP genotypes can be used for estimation of
breeding values for selection of livestock, crops, and forage species; for prediction of …

Understanding and predicting complex traits: knowledge from cattle

KE Kemper, ME Goddard - Human molecular genetics, 2012 - academic.oup.com
The genetic architecture of complex traits in cattle includes very large numbers of loci
affecting any given trait. Most of these loci have small effects but occasionally there are loci …

Reliability of genomic predictions across multiple populations

APW De Roos, BJ Hayes, ME Goddard - Genetics, 2009 - academic.oup.com
Genomic prediction of future phenotypes or genetic merit using dense SNP genotypes can
be used for prediction of disease risk, forensics, and genomic selection of livestock and …

Genomic prediction of genetic merit using LD-based haplotypes in the Nordic Holstein population

BCD Cuyabano, G Su, MS Lund - BMC genomics, 2014 - Springer
Background A haplotype approach to genomic prediction using high density data in dairy
cattle as an alternative to single-marker methods is presented. With the assumption that …

Improvement of prediction ability for genomic selection of dairy cattle by including dominance effects

C Sun, PM VanRaden, JB Cole, JR O'Connell - PloS one, 2014 - journals.plos.org
Dominance may be an important source of non-additive genetic variance for many traits of
dairy cattle. However, nearly all prediction models for dairy cattle have included only …

Accounting for dominance to improve genomic evaluations of dairy cows for fertility and milk production traits

H Aliloo, JE Pryce, O González-Recio… - Genetics Selection …, 2016 - Springer
Background Dominance effects may contribute to genetic variation of complex traits in dairy
cattle, especially for traits closely related to fitness such as fertility. However, traditional …

Within-and across-breed genomic prediction using whole-genome sequence and single nucleotide polymorphism panels

OOM Iheshiulor, JA Woolliams, X Yu… - Genetics Selection …, 2016 - Springer
Background Currently, genomic prediction in cattle is largely based on panels of about 54k
single nucleotide polymorphisms (SNPs). However with the decreasing costs of and current …

Genomic analysis of dominance effects on milk production and conformation traits in Fleckvieh cattle

J Ertl, A Legarra, ZG Vitezica, L Varona, C Edel… - Genetics Selection …, 2014 - Springer
Background Estimates of dominance variance in dairy cattle based on pedigree data vary
considerably across traits and amount to up to 50% of the total genetic variance for …

Application of genomics tools to animal breeding

J CM Dekkers - Current genomics, 2012 - ingentaconnect.com
The main goal in animal breeding is to select individuals that have high breeding values for
traits of interest as parents to produce the next generation and to do so as quickly as …

Genomic prediction using a reference population of multiple pure breeds and admixed individuals

E Karaman, G Su, I Croue, MS Lund - Genetics Selection Evolution, 2021 - Springer
Background In dairy cattle populations in which crossbreeding has been used, animals
show some level of diversity in their origins. In rotational crossbreeding, for instance …