BoNTs (botulinum neurotoxins), considered to be the most toxic of all biological substances,
inhibit neurotransmission through proteolytic cleavage of SNARE (soluble N-ethylmaleimide …

Botulinum neurotoxin type A (BoNT/A) is the most frequent cause of human botulism and, at
the same time, is largely used in human therapy. Some evidence indicates that it enters …

The clostridial neurotoxin family consists of tetanus neurotoxin and seven distinct botulinum
neurotoxins which cause the diseases tetanus and botulism. The extreme potency of these …

An overall picture of the botulinum toxins is provided, linking the recent developments in
their molecular and cellular aspects to the physiological actions. The pathophysiological …

Botulinum neurotoxins (BoNTs) are extremely potent neuromuscular poisons that act
through soluble N-ethylmaleimide-sensitive factor attachment protein receptor (SNARE) …

Botulinum neurotoxins (BoNTs) elicit flaccid paralysis through cleavage of SNARE proteins
within peripheral neurons. There are seven serotypes of the BoNTs, termed A− G, which …

Botulinum neurotoxins (BoNTs) are metalloprote-ases which act on nerve terminals and
cause a long-lasting inhibition of neurotransmitter release. BoNTs act by cleaving core …

Botulinum toxin is a uniquely potent substance whose natural site of action is the peripheral
cholinergic nerve ending. A substantial amount of information on the cellular, subcellular …

Botulinum neurotoxins (BoNTs) comprise seven distinct serotypes that inhibit the release of
neurotransmitter across neuromuscular junctions, resulting in potentially fatal flaccid …

Botulinum neurotoxin type B (BoNT/B) belongs to the family of botulinum neurotoxins, which
contains seven proteins (serotypes A to G). They act on the peripheral nervous system …