Normotensive young men (mean age 36 years) with positive (PFH)(n= 13) and negative (n=
29) family histories of hypertension were investigated in order to study systemic and renal …

We have previously described a subset of subjects with essential hypertension who fail to
appropriately modulate renal vascular and adrenal reactivity with changes in dietary sodium …

Relationships between renal haemodynamics and the renin-angiotensin system were
examined in 128 male adolescents with differing predispositions to hypertension. Baseline …

Objective An increased sensitivity to angiotensin II (Ang II) has been observed in patients
with established hypertension. In the current study we tested whether young normotensive …

Objectives An enhanced sensitivity to angiotensin II in the renal circulation has been
demonstrated in the pre-hypertensive phase both in the spontaneously hypertensive rat and …

Abstract Background and Methods. The kidney is important in blood-pressure regulation, but
its role in the development of essential hypertension is still subject to debate. We compared …

The responsiveness of plasma aldosterone to an angiotensin (Ang) II infusion was assessed
in normotensive young men, nine without and 13 with a family history of essential …

There is increasing evidence that a major site of production of angiotensin I and II is
peripheral tissue. Both angiotensin I and II are present in venous blood in amounts far too …

The natriuretic and intra-arterial blood pressure response to an acute saline load (1000 mL
0.9% NaCl), was studied in normotensive young men with positive (n= 11) and negative (n …

This study tested the hypothesis that gender affects the pressor and renal vasoconstrictor
responses to angiotensin (Ang) I and Ang II in salt-replete normotensive subjects. Ang I and …