Pathway analysis of genes identified through post-GWAS to underpin prostate cancer aetiology
Understanding the functional role of risk regions identified by genome-wide association
studies (GWAS) has made considerable recent progress and is referred to as the post …
studies (GWAS) has made considerable recent progress and is referred to as the post …
An integrative genomics approach for associating genome-wide association studies information with localized and metastatic prostate cancer phenotypes
C Hicks, R Ramani, O Sartor, R Bhalla… - Biomarker …, 2017 - journals.sagepub.com
High-throughput genotyping has enabled discovery of genetic variants associated with an
increased risk of developing prostate cancer using genome-wide association studies …
increased risk of developing prostate cancer using genome-wide association studies …
Comprehensive assessment and network analysis of the emerging genetic susceptibility landscape of prostate cancer
C Hicks, L Miele, T Koganti… - Cancer …, 2013 - journals.sagepub.com
Background Recent advances in high-throughput genotyping have made possible
identification of genetic variants associated with increased risk of developing prostate …
identification of genetic variants associated with increased risk of developing prostate …
In Silico Functional Pathway Annotation of 86 Established Prostate Cancer Risk Variants
LWM Loo, AYW Fong, I Cheng, L Le Marchand - Plos one, 2015 - journals.plos.org
Heritability is one of the strongest risk factors of prostate cancer, emphasizing the
importance of the genetic contribution towards prostate cancer risk. To date, 86 established …
importance of the genetic contribution towards prostate cancer risk. To date, 86 established …
Post-GWAS in prostate cancer: from genetic association to biological contribution
Genome-wide association studies (GWAS) have been successful in deciphering the genetic
component of predisposition to many human complex diseases including prostate cancer …
component of predisposition to many human complex diseases including prostate cancer …
Integrative pathway analysis of genome-wide association studies and gene expression data in prostate cancer
Background Pathway analysis of large-scale omics data assists us with the examination of
the cumulative effects of multiple functionally related genes, which are difficult to detect …
the cumulative effects of multiple functionally related genes, which are difficult to detect …
GWAS meets microarray: are the results of genome-wide association studies and gene-expression profiling consistent? Prostate cancer as an example
Background Genome-wide association studies (GWASs) and global profiling of gene
expression (microarrays) are two major technological breakthroughs that allow hypothesis …
expression (microarrays) are two major technological breakthroughs that allow hypothesis …
Integrative genomic analysis for the discovery of biomarkers in prostate cancer
Genome-wide association studies (GWAS) have achieved great success in identifying single
nucleotide polymorphisms (SNPs, herein called genetic variants) and genes associated with …
nucleotide polymorphisms (SNPs, herein called genetic variants) and genes associated with …
Post genome-wide association studies functional characterization of prostate cancer risk loci
Background Over the last decade, genome-wide association studies (GWAS) have
discovered many risk associated single nucleotide polymorphisms (SNPs) of prostate …
discovered many risk associated single nucleotide polymorphisms (SNPs) of prostate …
A review of prostate cancer genome-wide association studies (GWAS)
S Benafif, Z Kote-Jarai, RA Eeles - Cancer Epidemiology, Biomarkers & …, 2018 - AACR
Prostate cancer is the most common cancer in men in Europe and the United States. The
genetic heritability of prostate cancer is contributed to by both rarely occurring genetic …
genetic heritability of prostate cancer is contributed to by both rarely occurring genetic …
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