Neuroinflammation is a key player in Parkinson's disease and a prime target for therapy
L Qian, PM Flood, JS Hong - Journal of neural transmission, 2010 - Springer
Parkinson's disease (PD) is a neurodegenerative movement disorder characterized by the
progressive loss of dopaminergic neurons in the substantia nigra and depletion of dopamine …
progressive loss of dopaminergic neurons in the substantia nigra and depletion of dopamine …
[HTML][HTML] Neuroinflammation in Parkinson's disease and its potential as therapeutic target
Q Wang, Y Liu, J Zhou - Translational neurodegeneration, 2015 - Springer
Abstract Parkinson's disease (PD), the second most common age-associated
neurodegenerative disorder, is characterized by the loss of dopaminergic (DA) neurons and …
neurodegenerative disorder, is characterized by the loss of dopaminergic (DA) neurons and …
[HTML][HTML] Microglia mediated neuroinflammation in Parkinson's disease
S Isik, B Yeman Kiyak, R Akbayir, R Seyhali, T Arpaci - Cells, 2023 - mdpi.com
Parkinson's Disease (PD) is the second most common neurodegenerative disorder seen,
especially in the elderly. Tremor, shaking, movement problems, and difficulty with balance …
especially in the elderly. Tremor, shaking, movement problems, and difficulty with balance …
[HTML][HTML] Neuroinflammation and Parkinson's disease—From neurodegeneration to therapeutic opportunities
B Araújo, R Caridade-Silva, C Soares-Guedes… - Cells, 2022 - mdpi.com
Parkinson's disease (PD) is the second most prevalent neurodegenerative disorder
worldwide. Clinically, it is characterized by a progressive degeneration of dopaminergic …
worldwide. Clinically, it is characterized by a progressive degeneration of dopaminergic …
[HTML][HTML] Inflammation in Parkinson's disease: mechanisms and therapeutic implications
M Pajares, A I. Rojo, G Manda, L Boscá, A Cuadrado - Cells, 2020 - mdpi.com
Parkinson's disease (PD) is a common neurodegenerative disorder primarily characterized
by the death of dopaminergic neurons that project from the substantia nigra pars compacta …
by the death of dopaminergic neurons that project from the substantia nigra pars compacta …
Significant roles of neuroinflammation in Parkinson's disease: therapeutic targets for PD prevention
Glial cells outnumber neurons in the brain and play important roles in the neuroinflammation
that accompanies brain damage in neurodegenerative diseases. In Parkinson's disease …
that accompanies brain damage in neurodegenerative diseases. In Parkinson's disease …
Neuroinflammation in Parkinson's disease: its role in neuronal death and implications for therapeutic intervention
MG Tansey, MS Goldberg - Neurobiology of disease, 2010 - Elsevier
Parkinson's disease (PD) is the second most common neurodegenerative disease, after
Alzheimer's disease. The potential causes of PD remain uncertain, but recent studies …
Alzheimer's disease. The potential causes of PD remain uncertain, but recent studies …
[HTML][HTML] Neurodegeneration and neuroinflammation in Parkinson's disease: a self-sustained loop
Abstract Purpose of Review Neuroinflammation plays a significant role in Parkinson's
disease (PD) etiology along with mitochondrial dysfunction and impaired proteostasis. In this …
disease (PD) etiology along with mitochondrial dysfunction and impaired proteostasis. In this …
The role of neuroinflammation on the pathogenesis of Parkinson's disease
Parkinson's Disease (PD) is a common neurodegenerative disease characterized by the
progressive degeneration of nigrostriatal dopaminergic (DA) neurons. Although the …
progressive degeneration of nigrostriatal dopaminergic (DA) neurons. Although the …
Microglia in Parkinson's disease
MS Ho - Neuroglia in neurodegenerative diseases, 2019 - Springer
Microglia are the most abundant immune cells in the central nervous system (CNS), where
they interact with neurons and exhibit a wide array of functions in physiological and …
they interact with neurons and exhibit a wide array of functions in physiological and …