Differential effects on expression of IL‐2 receptors (p55 and p70) by the HTLV‐I pX DNA

H Sabe, A Tanaka, H Siomi, S Koyasu… - … journal of cancer, 1988 - Wiley Online Library
Abnormal expression of the low‐affinity receptor for inter‐leukin‐2 (IL‐2R) is a characteristic
of the HTLV‐I (+) leukemic T cells in adult T‐cell leukemia (ATL). Despite the expression of …

IL-2-dependent ATL cell lines with phenotypes differing from the original leukemia cells

Y Yamada, Y Nagata, S Kamihira, M Tagawa… - Leukemia research, 1991 - Elsevier
Adult T-cell leukemia (ATL) cells have been shown to express the receptor for IL-2 by
studies using anti-CD25 monoclonal antibody, but these cells usually show no or only a …

Adult T leukemia cells produce a lymphokine that augments interleukin 2 receptor expression.

K Teshigawara, M Maeda, K Nishino… - The Journal of …, 1985 - europepmc.org
Human T-cell leukemia virus (HTLV)-infected cell lines derived from adult T-cell leukemia
(ATL) express constitutively the receptor for Interleukin-2 (IL-2-R) and the associated antigen …

Interleukin‐2 receptor β‐chain (p70–75) expressed on leukemic cells from adult T cell leukemia patients

T Kodaka, T Uchiyama, T Ishikawa… - Japanese journal of …, 1990 - Wiley Online Library
To determine whether the interleukin‐2 receptor (IL‐2R) β‐chain (p70–75) is expressed on
lenkemic cells from patients with adult T cell leukemia (ATL) as well as α‐chain (p55, Tac) …

Lack of interleukin-2 (IL-2) dependent growth of TAC positive T-ALL/NHL cells is due to the expression of only low affinity receptors for IL-2

KM Debatin, C Woodroofe, H Lahm… - … : official journal of …, 1989 - epub.uni-regensburg.de
Binding of interleukin-2 (IL-2) to high affinity receptors on activated normal T cells was
shown to be the essential step in induction of proliferation of such cells. The finding of …

Close association between interleukin 2 receptor mRNA expression and human T cell leukemia/lymphoma virus type I viral RNA expression in short-term cultured …

H Umadome, T Uchiyama, T Hori… - The Journal of …, 1988 - Am Soc Clin Investig
Human T cell leukemia/lymphoma (T-lymphotropic) virus type I (HTLV-I) infection has been
considered to be closely associated with the leukemogenesis of adult T cell leukemia (ATL) …

Establishment of an interleukin 2-dependent human T cell line from a patient with T cell chronic lymphocytic leukemia who is not infected with human T cell leukemia …

T Hori, T Uchiyama, M Tsudo, H Umadome, H Ohno… - 1987 - ashpublications.org
We established an interleukin 2 (IL-2)-dependent human T cell line, Kit 225, from a patient
with T cell chronic lymphocytic leukemia (T-CLL) with OKT3+,-T4+,-T8-phenotype. Southern …

Establishment of an IL‐2 independent, human T‐cell line possessing only the p70 IL‐2 receptor

G Starkebaum, TP Loughran JR… - … journal of cancer, 1991 - Wiley Online Library
A continuous cell line was established from the blood of a patient (HH) with an aggressive
cutaneous T‐cell leukemia/lymphoma who lacked antibodies to human T lymphotrophic …

Interleukin 2 receptor (Tac antigen) expression in HTLV-I-associated adult T-cell leukemia

TA Waldmann, DL Longo, WJ Leonard, JM Depper… - Cancer Research, 1985 - AACR
Abstract Interleukin-2 (IL-2) is a lymphokine synthesized by some T-cells following
activation. Resting T-cells do not express IL-2 receptors, but receptors are rapidly expressed …

[HTML][HTML] Evidence for the interleukin-2 dependent expansion of leukemic cells in adult T cell leukemia

M Maeda, N Arima, Y Daitoku, M Kashihara… - Blood, 1987 - Elsevier
Interleukin 2 (IL-2) receptor/Tac antigen is abnormally expressed on cells of patients with
adult T cell leukemia (ATL) caused by infection with human T lymphotropic virus type I …