Matrine-family alkaloids: versatile precursors for bioactive modifications

X Cai, H Zhang, B Xie - Medicinal Chemistry, 2020 - ingentaconnect.com
Matrine-family alkaloids as tetracycloquinolizindine analogues from Traditional Chinese
Medicine Sophora flavescens Ait, Sophora subprostrata and Sophora alopecuroides L …

Structural modifications of matrine-type alkaloids

XH Cai, H Guo, B Xie - Mini Reviews in Medicinal Chemistry, 2018 - ingentaconnect.com
Matrine-type alkaloids belong to quinolizidine analogues from Sophora flavescens Ait,
Sophora subprostrata and Sophora alopecuroides L. possess numerous therapeutic …

[HTML][HTML] Research progress of natural matrine compounds and synthetic matrine derivatives

J Li, S Wei, D Marabada, Z Wang, Q Huang - Molecules, 2023 - mdpi.com
Matrine is a quinoline alkaloid extracted and separated from the dried root, fruit, and other
parts of the plant Sophora flavescens using an organic solvent. Matrine exhibits a variety of …

Matrine: Bioactivities and structural modifications

J Huang, H Xu - Current Topics in Medicinal Chemistry, 2016 - ingentaconnect.com
Matrine is a quinolizidine alkaloid isolated from the roots of Sophora flavescens (Kushen),
Sophora tonkinensis, and Sophora alopecuroides (Kudouzi). Matrine and its derivatives …

The advances in bioactivities, mechanisms of action and structural optimizations of matrine and its derivatives

J Xu, M Lv, H Xu - Mini Reviews in Medicinal Chemistry, 2022 - ingentaconnect.com
Matrine, a tetracyclo-quinolizidine alkaloid, is isolated from the industrial crop plant Sophora
flavescens. Due to a wide range of pharmacological and agricultural properties, the …

[HTML][HTML] Matrine family derivatives: Synthesis, reactions procedures, mechanism, and application in medicinal, agricultural, and materials chemistry

JAH Kowah, R Gao, F Li, C Guang, M Jiang… - European Journal of …, 2023 - Elsevier
Matrine alkaloid is a type of Sophora flavescens (Ku Shen) found in plants. It holds excellent
applications for anticancer, antimicrobials, antibacterial, anti pests, and other applications in …

Research progress of agricultural bioactivities and structural modifications of matrine and its analogues

Z Bingchuan, XU Hui - Chinese Journal of Pesticide Science, 2019 - nyxxb.cn
Matrine and its analogues are a kind of alkaloids isolated from Sophora flavescens and
Sophora alopecuroides. They have exhibited a broad scope of medical (eg, anticancer, anti …

A pyridine dearomatization approach to the matrine-type lupin alkaloids

JK Kerkovius, A Stegner, A Turlik, PH Lam… - Journal of the …, 2022 - ACS Publications
(+)-Matrine and (+)-isomatrine are tetracyclic alkaloids isolated from the plant Sophora
flavescens, the roots of which are used in traditional Chinese medicine. Biosynthetically …

Structurally Diverse Matrine‐Based Alkaloids with Anti‐inflammatory Effects from Sophora alopecuroides

D Luo, NH Chen, WZ Wang, JH Zhang… - Chinese Journal of …, 2021 - Wiley Online Library
Main observation and conclusion A phytochemical investigation on the seeds of Sophora
alopecuroides led to obtaining fourteen structurally diverse matrine‐based alkaloids (1 …

Synthetic Study of Matrine-Type Alkaloids: Stereoselective Construction of the AB Rings of the Quinolizidine Skeleton

C Tsukano, A Oimura, I Enkhtaivan, Y Takemoto - Synlett, 2014 - thieme-connect.com
A new method has been developed for the stereoselective construction of the AB rings of the
quinolizidine skeleton of matrine-type alkaloids with a cis-cis stereochemistry. The key …