β-Sitosterol inhibits cell growth and induces apoptosis in SGC-7901 human stomach cancer cells

Y Zhao, SKC Chang, G Qu, T Li… - Journal of agricultural and …, 2009 - ACS Publications
β-Sitosterol is an important phytosterol found in plant food. It has been shown to have
antiproliferative effects on cancers of the colon, breast, and prostate, but its effect on …

β-Sitosterol induces anti-proliferation and apoptosis in human leukemic U937 cells through activation of caspase-3 and induction of Bax/Bcl-2 ratio

C Park, DO Moon, CH Rhu, BT Choi… - Biological and …, 2007 - jstage.jst.go.jp
accepted March 6, 2007 b-Sitosterol is the main dietary phytosterol found in plants and has
been shown to inhibit proliferation and induce apoptosis in human solid tumors such as …

Induction of Bax and activation of caspases during β-sitosterol-mediated apoptosis in human colon cancer cells

YH Choi, KR Kong, Y Kim… - International …, 2003 - spandidos-publications.com
Abstract β-sitosterol, a main dietary phytosterol found in plants, may have the potential for
prevention and therapy for human cancer. The purpose of the present study was to examine …

β-Sitosterol activates Fas signaling in human breast cancer cells

AB Awad, M Chinnam, CS Fink, PG Bradford - Phytomedicine, 2007 - Elsevier
β-Sitosterol is the most abundant phytosterol. Phytosterols are enriched in legumes, oil
seeds and unrefined plant oils as found in foods such as peanut butter, pistachios and …

[HTML][HTML] Molecular mechanism of β-sitosterol and its derivatives in tumor progression

X Bao, Y Zhang, H Zhang, L Xia - Frontiers in oncology, 2022 - frontiersin.org
β-Sitosterol (SIT), a white powdery organic substance with a molecular formula of C29H50O,
is one of the most abundant naturally occurring phytosterols in plants. With a chemical …

Apoptogenic effects of β-sitosterol glucoside from Castanopsis indica leaves

N Dolai, A Kumar, A Islam, PK Haldar - Natural product research, 2016 - Taylor & Francis
β-Sitosterol glucoside (BSSG) is a natural biologically active substance isolated from the
Castanopsis indica leaves. This study explored the apoptogenic mechanistic studies of …

Apoptotic effect of a phytosterol-ingredient and its main phytosterol (β-sitosterol) in human cancer cell lines

A Alvarez-Sala, A Attanzio, L Tesoriere… - … journal of food …, 2019 - Taylor & Francis
Dietary interventions may effectively control cancer development, with phytosterols (PS)
being a class of cancer chemopreventive dietary phytochemicals. The present study, for the …

[HTML][HTML] β-sitosterol induces reactive oxygen species-mediated apoptosis in human hepatocellular carcinoma cell line

MJ Ditty, D Ezhilarasan - Avicenna Journal of Phytomedicine, 2021 - ncbi.nlm.nih.gov
Objective: It is of interest to investigate the anti-proliferative effect of β-sitosterol (BS) on
human hepatocellular carcinoma (HepG2) cell line. Materials and Methods: β-sitosterol …

[PDF][PDF] Anticancer potential of β-sitosterol

L Novotny, ME Abdel-Hamid… - Int. J. Clin. Pharmacol …, 2017 - researchgate.net
Introduction β-Sitosterol (beta-sitosterol; Figure1) is a natural phytosterol. It is a steroidal
molecule similar to cholesterol (Figure 2) but is of a plant origin. Because of its steroidal …

γ-Sitosterol from Acacia nilotica L. induces G2/M cell cycle arrest and apoptosis through c-Myc suppression in MCF-7 and A549 cells

S Sundarraj, R Thangam, V Sreevani, K Kaveri… - Journal of …, 2012 - Elsevier
ETHNOPHARMACOLOGICAL RELEVANCE: Acacia nilotica is widely distributed in Asia. In
India, it occupies an important place in the indigenous system of medicine against anti …