Background Hafnium oxide, NBTXR3 nanoparticles were designed for high dose energy
deposition within cancer cells when exposed to ionizing radiation. The purpose of this study …

Purpose The side effects of radiotherapy induced on healthy tissue limit its use. To
overcome this issue and fully exploit the potential of radiotherapy to treat cancers, the first-in …

Since the discovery of cisplatin about 40 years ago, the design of innovative metal-based
anticancer drugs is a growing area of research. Transition metal coordination complexes …

Aim: There is considerable interest in approaches that could improve the therapeutic
window of radiotherapy. In this study, hafnium oxide nanoparticles were designed that …

Purpose Despite tremendous results achieved by immune checkpoint inhibitors, most
patients are not responders, mainly because of the lack of a pre-existing anti-tumor immune …

Purpose Clinical evidence of the radiation-enhancing effects of nanoparticles has emerged.
Materials and methods We searched the literature in English and French on PubMed up to …

Objective: Radiosensitisation caused by titanium dioxide nanoparticles (TiO 2-NPs) is
investigated using phantoms (PRESAGE® dosimeters) and in vitro using two types of cell …

Materials with a high atomic number (Z) are shown to cause an increase in the level of cell
kill by ionizing radiation when introduced into tumor cells. This study uses in vitro …

Nanoparticles of high atomic number (Z) materials can act as radiosensitizers to enhance
radiation dose delivered to tumors. An analytical approach is used to calculate dose …

Background Biological applications of nanoparticles are rapidly increasing, which
introduces new possibilities to improve the efficacy of radiotherapy. Here, we synthesized …