[HTML][HTML] Metal-based nanoenhancers for future radiotherapy: radiosensitizing and synergistic effects on tumor cells

Y Liu, P Zhang, F Li, X Jin, J Li, W Chen, Q Li - Theranostics, 2018 - ncbi.nlm.nih.gov
Radiotherapy is one of the major therapeutic strategies for cancer treatment. In the past
decade, there has been growing interest in using high Z (atomic number) elements …

Optimising element choice for nanoparticle radiosensitisers

SJ McMahon, H Paganetti, KM Prise - Nanoscale, 2016 - pubs.rsc.org
There is considerable interest in the use of heavy atom nanoparticles as theranostic contrast
agents due to their high radiation cross-section compared to soft tissue. However, published …

Radiolabeled nanobodies as theranostic tools in targeted radionuclide therapy of cancer

M D'Huyvetter, C Xavier, V Caveliers… - Expert opinion on …, 2014 - Taylor & Francis
Introduction: The integration of diagnostic testing for the presence of a molecular target is of
interest to predict successful targeted radionuclide therapy (TRNT). This so-called …

Platinum nanoparticles: An exquisite tool to overcome radioresistance

S Li, E Porcel, H Remita, S Marco, M Réfrégiers… - Cancer …, 2017 - Springer
Backgroud Small metallic nanoparticles are proposed as potential nanodrugs to optimize
the performances of radiotherapy. This strategy, based on the enrichment of tumours with …

X-Ray responsive nanoparticles with triggered release of nitrite, a precursor of reactive nitrogen species, for enhanced cancer radiosensitization

F Liu, J Lou, D Hristov - Nanoscale, 2017 - pubs.rsc.org
Remotely and locally triggered release of therapeutic species by X-ray irradiation is highly
desired to enhance the efficacy of radiotherapy. However, the development of such X-ray …

Radio-enhancement effects by radiolabeled nanoparticles

YH Gholami, R Maschmeyer, Z Kuncic - Scientific Reports, 2019 - nature.com
In cancer radiation therapy, dose enhancement by nanoparticles has to date been
investigated only for external beam radiotherapy (EBRT). Here, we report on an in silico …

In vivo demonstration of enhanced radiotherapy using rare earth doped titania nanoparticles

HE Townley, J Kim, PJ Dobson - Nanoscale, 2012 - pubs.rsc.org
Radiation therapy is often limited by damage to healthy tissue and associated side-effects;
restricting radiation to ineffective doses. Preferential incorporation of materials into tumour …

The radiosensitization effect of titanate nanotubes as a new tool in radiation therapy for glioblastoma: a proof-of-concept

C Mirjolet, AL Papa, G Créhange, O Raguin… - Radiotherapy and …, 2013 - Elsevier
Background and purpose One of the new challenges to improve radiotherapy is to increase
the ionizing effect by using nanoparticles. The interest of titanate nanotubes (TiONts) …

Advances of nanomedicine in radiotherapy

W Liu, B Chen, H Zheng, Y Xing, G Chen, P Zhou… - Pharmaceutics, 2021 - mdpi.com
Radiotherapy (RT) remains one of the current main treatment strategies for many types of
cancer. However, how to improve RT efficiency while reducing its side effects is still a large …

Hafnium-doped hydroxyapatite nanoparticles with ionizing radiation for lung cancer treatment

MH Chen, N Hanagata, T Ikoma, JY Huang, KY Li… - Acta biomaterialia, 2016 - Elsevier
Recently, photodynamic therapy (PDT) is one of the new clinical options by generating
cytotoxic reactive oxygen species (ROS) to kill cancer cells. However, the optical approach …