Contributing to the on-going debate around the clinical application of preimplantation embryo selection based on polygenic risk scores (PGT-P)
P Makrythanasis, G Kakourou, T Mamas… - European Journal of …, 2023 - nature.com
The article by Siermann et al.[1] in this issue presents the findings of a questionnaire-based
survey of 31 health care professionals (HCPs) involved in Preimplantation Genetic Testing …
survey of 31 health care professionals (HCPs) involved in Preimplantation Genetic Testing …
Ready for polygenic risk scores? An analysis of regulation of preimplantation genetic testing in European countries
M Siermann, V van der Schoot, EM Bunnik… - Human …, 2024 - academic.oup.com
STUDY QUESTION Would the different regulatory approaches for preimplantation genetic
testing (PGT) in Europe permit the implementation of preimplantation genetic testing using …
testing (PGT) in Europe permit the implementation of preimplantation genetic testing using …
Limitations, concerns and potential: attitudes of healthcare professionals toward preimplantation genetic testing using polygenic risk scores
M Siermann, O Valcke, JR Vermeesch… - European Journal of …, 2023 - nature.com
Preimplantation genetic testing using polygenic risk scores (PGT-P) has recently been
introduced. However, PGT-P has been met with many ethical concerns. It is therefore …
introduced. However, PGT-P has been met with many ethical concerns. It is therefore …
Clinical utility of polygenic risk scores for embryo selection: a points to consider statement of the American College of Medical Genetics and Genomics (ACMG)
Polygenic risk score (PRS) assessment for embryo selection (hereafter referred to as
preimplantation testing for polygenic disorder [PGT-P]) is an emerging reproductive …
preimplantation testing for polygenic disorder [PGT-P]) is an emerging reproductive …
The use of polygenic risk scores in pre-implantation genetic testing: an unproven, unethical practice
F Forzano, O Antonova, A Clarke, G de Wert… - European Journal of …, 2022 - nature.com
Polygenic risk score analyses on embryos (PGT-P) are being marketed by some private
testing companies to parents using in vitro fertilisation as being useful in selecting the …
testing companies to parents using in vitro fertilisation as being useful in selecting the …
P-337 Ready for polygenic risk scores? An analysis of regulation of preimplantation genetic testing in seven European countries
M Siermann, V Van der Schoot, E Bunnik… - Human …, 2024 - academic.oup.com
Study question Would the different regulatory approaches for preimplantation genetic testing
(PGT) in Europe permit the implementation of preimplantation genetic testing using …
(PGT) in Europe permit the implementation of preimplantation genetic testing using …
“Are we not going too far?“: Socio-ethical considerations of preimplantation genetic testing using polygenic risk scores according to healthcare professionals
M Siermann, O Valcke, JR Vermeesch, T Raivio… - Social Science & …, 2024 - Elsevier
The recent introduction of polygenic risk scores within preimplantation genetic testing (PGT-
P) has been met with many concerns. To get more insights into the perspectives of relevant …
P) has been met with many concerns. To get more insights into the perspectives of relevant …
Perspectives of preimplantation genetic testing patients in Belgium on the ethics of polygenic embryo screening
M Siermann, JR Vermeesch, T Raivio, A Vanhie… - Reproductive …, 2024 - Elsevier
Research question What are the perspectives of preimplantation genetic testing (PGT)
patients in Belgium on the ethics of PGT for polygenic risk scoring (PGT-P)? Design In-depth …
patients in Belgium on the ethics of PGT for polygenic risk scoring (PGT-P)? Design In-depth …
[HTML][HTML] A review of normative documents on preimplantation genetic testing: recommendations for PGT-P
M Siermann, O Tšuiko, JR Vermeesch, T Raivio… - Genetics in …, 2022 - Elsevier
Purpose Recently, preimplantation genetic testing (PGT) for polygenic conditions (PGT-P)
has been introduced commercially. In view of the lack of specific guidance on this …
has been introduced commercially. In view of the lack of specific guidance on this …
Correction: The use of polygenic risk scores in pre-implantation genetic testing: an unproven, unethical practice
F Forzano, O Antonova, A Clarke, G de Wert… - European Journal of …, 2022 - nature.com
The article “The use of polygenic risk scores in pre-implantation genetic testing: an
unproven, unethical practice”, written by Francesca Forzano et al., was originally published …
unproven, unethical practice”, written by Francesca Forzano et al., was originally published …
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