First discovered as orphan receptors, liver X receptors (LXRs) were subsequently identified
as the nuclear receptor target of the cholesterol metabolites, oxysterols. There are 2 LXR …

Liver X receptors (LXR) are oxysterol-activated nuclear receptors that play a central role in
reverse cholesterol transport through up-regulation of ATP-binding cassette transporters …

Liver X receptors (LXRα and LXRβ) are nuclear receptors, which are important regulators of
cholesterol and lipid metabolism. LXRs control genes involved in cholesterol efflux in …

IL-5 stimulates production of T15/EO6 IgM antibodies that can block the uptake of oxidized
low density lipoprotein by macrophages, whereas a deficiency in macrophage IL-5 …

Background—Liver X receptors (LXRs) are ligand-activated transcription factors involved in
the control of lipid metabolism and inflammation. Synthetic LXR agonists have been shown …

The liver X receptors (LXRs) are members of the nuclear receptor superfamily that regulate
sterol metabolism and inflammation. We sought to identify previously unknown genes …

The nuclear oxysterol receptors LXRα (NR1H3) and LXRβ (NR1H2) coordinately regulate
the expression of genes involved in the transport and catabolism of cholesterol. In …

Recent studies on the liver X receptor-α (LXR-α) have recognized its crucial protective role
in the initiation of a cross-talk between lipid metabolism and inflammation regarded as a …

The liver X receptor (LXR) signaling pathway is an important modulator of atherosclerosis,
but the relative importance of the two LXRs in atheroprotection is incompletely understood …

The liver X receptors (LXRs) are nuclear receptors activated by oxysterols that are now
recognized to play an important role in the control of lipid homeostasis. LXRs have been …