Liver X receptors α (LXRα) and β (LXRβ) are essential for protection against cardiovascular
diseases. LXRs are members of the nuclear receptor superfamily of DNA-binding …

The nuclear receptors Liver X receptors, LXRα and LXRβ, regulate cholesterol and
triglyceride metabolism. We and others have previously reported that synthetic LXR agonists …

The liver X receptors α and β (LXRα and LXRβ) are important regulators of cholesterol
homeostasis in liver and macrophages. Synthetic LXR ligands prevent the development of …

Liver X receptors (LXRs) are ligand-dependent transcription factors that are activated by
metabolites of cholesterol, oxysterols, and a number of synthetic agonists. LXRs play potent …

The liver X receptors (LXRα and LXRβ) are nuclear receptor transcription factors that are
activated by certain oxysterol derivatives of cholesterol. As such, LXR activity may be up …

The liver X receptors (LXRs) are ligand-activated transcription factors belonging to the
nuclear hormone receptor superfamily. Since their initial identification more than a decade …

Liver X receptor (LXR)-α and-β play a major role in lipid and glucose homeostasis. Their
expression and function in the heart is not well characterized. Our aim was to describe the …

Liver X receptors (LXRs) are nuclear receptors that play a central role in cholesterol
metabolism. When activated, LXRs induce a series of genes that are involved in cholesterol …

Background The nuclear receptor liver X receptor (LXR) has two isoforms: LXRα and LXRβ.
LXR activation promotes cholesterol efflux in macrophages, but the relative importance of …

The Liver X Receptors, LXRα and LXRβ are members of the nuclear hormone receptor
superfamily which have recently been implicated as novel pharmacological targets for the …