The Personalized Nutrition Study (POINTS): evaluation of a genetically informed weight loss approach, a Randomized Clinical Trial

C Höchsmann, S Yang, JM Ordovás, JL Dorling… - Nature …, 2023 - nature.com
Weight loss (WL) differences between isocaloric high-carbohydrate and high-fat diets are
generally small; however, individual WL varies within diet groups. Genotype patterns may …

[HTML][HTML] Effect of low-fat vs low-carbohydrate diet on 12-month weight loss in overweight adults and the association with genotype pattern or insulin secretion: the …

CD Gardner, JF Trepanowski, LC Del Gobbo… - Jama, 2018 - jamanetwork.com
Importance Dietary modification remains key to successful weight loss. Yet, no one dietary
strategy is consistently superior to others for the general population. Previous research …

DIETFITS study (diet intervention examining the factors interacting with treatment success)–Study design and methods

MV Stanton, JL Robinson, SM Kirkpatrick… - Contemporary clinical …, 2017 - Elsevier
Numerous studies have attempted to identify successful dietary strategies for weight loss,
and many have focused on Low-Fat vs. Low-Carbohydrate comparisons. Despite relatively …

Tailoring dietary approaches for weight loss

CD Gardner - International journal of obesity supplements, 2012 - nature.com
Abstract Although the 'Low-Fat'diet was the predominant public health recommendation for
weight loss and weight control for the past several decades, the obesity epidemic continued …

Differences in weight loss between persons on standard balanced vs nutrigenetic diets in a randomized controlled trial

KA Frankwich, J Egnatios, ML Kenyon… - Clinical …, 2015 - Elsevier
Background & Aims Many companies provide genetic tests for obesity-related
polymorphisms (nutrigenetics) and make dietary recommendations for weight loss that are …

Genetic variation of fasting glucose and changes in glycemia in response to 2-year weight-loss diet intervention: the POUNDS LOST trial

T Wang, T Huang, Y Zheng, J Rood, GA Bray… - International journal of …, 2016 - nature.com
Objective: Weight-loss intervention through diet modification has been widely used to
improve obesity-related hyperglycemia; however, little is known about whether genetic …

Toward precision weight-loss dietary interventions: findings from the POUNDS lost trial

L Qi, Y Heianza, X Li, FM Sacks, GA Bray - Nutrients, 2023 - mdpi.com
The POUNDS Lost trial is a 2-year clinical trial testing the effects of dietary interventions on
weight loss. This study included 811 adults with overweight or obesity who were randomized …

Improved weight management using genetic information to personalize a calorie controlled diet

I Arkadianos, AM Valdes, E Marinos, A Florou, RD Gill… - Nutrition journal, 2007 - Springer
Background Gene-environment studies demonstrate variability in nutrient requirements
depending upon individual variations in genes affecting nutrient metabolism and transport …

[PDF][PDF] Genotype-dependent response to energy-restricted diets in obese subjects: towards personalized nutrition.

JA Martínez, MD Parra, JL Santos… - Asia Pacific journal of …, 2008 - researchgate.net
Obesity is a complex disease, which in many cases appears as a polygenic condition
affected by environmental factors (mainly unbalanced dietary patterns and physical …

Individualized weight management: what can be learned from nutrigenomics and nutrigenetics?

I Rudkowska, L Pérusse - Progress in molecular biology and translational …, 2012 - Elsevier
The rise in the prevalence of obesity observed over the past decades is taken by many as an
indication of the predominance of environmental factors (the so-called obesogenic …