[HTML][HTML] Increased toll-like receptors and p53 levels regulate apoptosis and angiogenesis in non-muscle invasive bladder cancer: mechanism of action of P-MAPA …
Background The new modalities for treating patients with non-muscle invasive bladder
cancer (NMIBC) for whom BCG (Bacillus Calmette-Guerin) has failed or is contraindicated …
cancer (NMIBC) for whom BCG (Bacillus Calmette-Guerin) has failed or is contraindicated …
OncoTherad®(MRB-CFI-1) nano-immunotherapy reduced tumoral progression in non-muscle invasive bladder cancer through activation of Toll-like signaling pathway
IB Reis, LHS Tibo, EAR Socca, BR De Souza, N Durán… - Tissue and Cell, 2022 - Elsevier
The new modalities for treating patients with high-grade non-muscle invasive bladder
cancer (HGNMIBC) for whom Bacillus Calmette-Guerin (BCG) has failed or is …
cancer (HGNMIBC) for whom Bacillus Calmette-Guerin (BCG) has failed or is …
Tumor-associated macrophage enhances PD-L1-mediated immune escape of bladder cancer through PKM2 dimer-STAT3 complex nuclear translocation
Y Yu, Y Liang, F Xie, Z Zhang, P Zhang, X Zhao… - Cancer Letters, 2024 - Elsevier
Tumor-associated macrophages (TAMs) are important components of the tumor
microenvironment (TME) and strongly associated with poor prognosis and drug resistance …
microenvironment (TME) and strongly associated with poor prognosis and drug resistance …
NF-κB inhibitor, BAY11-7082, suppresses M2 tumor-associated macrophage induced EMT potential via miR-30a/NF-κB/Snail signaling in bladder cancer cells
Q Zhang, Z Mao, J Sun - Gene, 2019 - Elsevier
Background Chronic inflammatory microenvironment has been shown to play a key role in
initiating tumorigenesis and facilitating malignant progression. Primary tumors surrounded …
initiating tumorigenesis and facilitating malignant progression. Primary tumors surrounded …
Role of OncoTherad immunotherapy in the regulation of toll-like receptors-mediated immune system and RANK/RANKL signaling: New therapeutic perspective for …
e16004 Background: The new modalities for treating patients with non-muscle invasive
bladder cancer (NMIBC) for whom Bacillus Calmette-Guerin (BCG) has failed or is …
bladder cancer (NMIBC) for whom Bacillus Calmette-Guerin (BCG) has failed or is …
A novel therapeutic strategy for non-muscle invasive bladder cancer: OncoTherad® immunotherapy associated with platelet-rich plasma
BR de Souza, IB Reis, GC de Arruda Camargo… - International …, 2023 - Elsevier
Patients with non-muscle invasive bladder cancer (NMIBC) that are unresponsive to Bacillus
Calmette-Guérin (BCG) have historically had limited treatment options. A new perspective is …
Calmette-Guérin (BCG) have historically had limited treatment options. A new perspective is …
A feed-forward loop based on aerobic glycolysis and TGF-β between tumor-associated macrophages and bladder cancer cells promoted malignant progression and …
C Shen, J Liu, W Jiao, X Zhang, X Zhao, X Yang… - Journal of Cancer …, 2023 - Springer
Purpose Immunotherapy with programmed cell death 1/ligand 1 (PD-1/PD-L1) checkpoint
inhibitors has revolutionized the systemic treatment of solid tumors, including bladder …
inhibitors has revolutionized the systemic treatment of solid tumors, including bladder …
[HTML][HTML] EGCG enhanced the anti-tumor effect of doxorubicine in bladder cancer via NF-κB/MDM2/p53 pathway
KW Luo, X Zhu, T Zhao, J Zhong, H Gao… - Frontiers in cell and …, 2020 - frontiersin.org
Doxorubicin (DOX), the first-line chemotherapy for bladder cancer, usually induces side
effects. We previously demonstrated that green tea polyphenol EGCG had potent anti-tumor …
effects. We previously demonstrated that green tea polyphenol EGCG had potent anti-tumor …
[HTML][HTML] Unveiling the molecular mechanisms driving the capsaicin-induced immunomodulatory effects on PD-L1 expression in bladder and renal cancer cell lines
MB Morelli, O Marinelli, C Aguzzi, L Zeppa, M Nabissi… - Cancers, 2022 - mdpi.com
Simple Summary Over time, capsaicin (CPS) has been considered both a potential anti-
cancer and pro-cancer molecule. Hence, the diversity of CPS functioning has already been …
cancer and pro-cancer molecule. Hence, the diversity of CPS functioning has already been …
OncoTherad® is an immunomodulator of biological response that downregulate RANK/RANKL signaling pathway and PD-1/PD-L1 immune checkpoint in non …
IB Reis, LHS Tibo, BR de Souza, N Durán… - Journal of Cancer …, 2023 - Springer
Intoduction Bladder cancer is the second most common urinary tract cancer. Above 70% of
the occurrence of bladder cancer is superficial (pTis, pTa, and pT1), non-muscle invasive …
the occurrence of bladder cancer is superficial (pTis, pTa, and pT1), non-muscle invasive …
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