Mitochondria autophagy: a potential target for cancer therapy
YH Qiu, TS Zhang, XW Wang, M Wang… - Journal of drug …, 2021 - Taylor & Francis
Mitophagy is a selective form of macroautophagy in which dysfunctional and damaged
mitochondria can be efficiently degraded, removed and recycled through autophagy …
mitochondria can be efficiently degraded, removed and recycled through autophagy …
[HTML][HTML] The role of mitochondrial dynamics and mitophagy in carcinogenesis, metastasis and therapy
Y Wang, HH Liu, YT Cao, LL Zhang… - Frontiers in Cell and …, 2020 - frontiersin.org
Mitochondria are key cellular organelles and play vital roles in energy metabolism,
apoptosis regulation and cellular homeostasis. Mitochondrial dynamics refers to the varying …
apoptosis regulation and cellular homeostasis. Mitochondrial dynamics refers to the varying …
[HTML][HTML] Autophagy/mitophagy regulated by ubiquitination: a promising pathway in cancer therapeutics
SC Jee, H Cheong - Cancers, 2023 - mdpi.com
Simple Summary Autophagy and mitophagy are important processes in the regulation of
cancer progression. Although autophagy and mitophagy have dual roles in cancer, targeting …
cancer progression. Although autophagy and mitophagy have dual roles in cancer, targeting …
[HTML][HTML] Mitophagy and cancer
AH Chourasia, ML Boland, KF Macleod - Cancer & metabolism, 2015 - Springer
Mitophagy is a selective form of macro-autophagy in which mitochondria are selectively
targeted for degradation in autophagolysosomes. Mitophagy can have the beneficial effect …
targeted for degradation in autophagolysosomes. Mitophagy can have the beneficial effect …
The emerging, multifaceted role of mitophagy in cancer and cancer therapeutics
Mitophagy is an evolutionarily conserved cellular process which selectively eliminates
dysfunctional mitochondria by targeting them to the autophagosome for degradation …
dysfunctional mitochondria by targeting them to the autophagosome for degradation …
Regulation and function of mitophagy in development and cancer
Beyond its role in recycling intracellular components nonselectively to sustain survival in
response to metabolic stresses, autophagy can also selectively degrade specific cargoes …
response to metabolic stresses, autophagy can also selectively degrade specific cargoes …
Mitophagy: Link to cancer development and therapy
AV Kulikov, EA Luchkina, V Gogvadze… - … and biophysical research …, 2017 - Elsevier
Mitophagy, the selective degradation of mitochondria via the autophagic pathway, is a vital
mechanism of mitochondrial quality control in cells. Mitophagy is responsible for the removal …
mechanism of mitochondrial quality control in cells. Mitophagy is responsible for the removal …
[HTML][HTML] Mitophagy in carcinogenesis and cancer treatment
TV Denisenko, V Gogvadze, B Zhivotovsky - Discover Oncology, 2021 - Springer
In order to maintain a functional mitochondrial network, cells have developed a quality
control mechanism, namely mitophagy. This process can be induced through different …
control mechanism, namely mitophagy. This process can be induced through different …
Mitophagy: A novel perspective for insighting into cancer and cancer treatment
C Song, S Pan, J Zhang, N Li, Q Geng - Cell Proliferation, 2022 - Wiley Online Library
Background Mitophagy refers to the selective self‐elimination of mitochondria under
damaged or certain developmental conditions. As an important regulatory mechanism to …
damaged or certain developmental conditions. As an important regulatory mechanism to …
[HTML][HTML] Mitophagy in cancer: a tale of adaptation
M Vara-Perez, B Felipe-Abrio, P Agostinis - Cells, 2019 - mdpi.com
In the past years, we have learnt that tumors co-evolve with their microenvironment, and that
the active interaction between cancer cells and stromal cells plays a pivotal role in cancer …
the active interaction between cancer cells and stromal cells plays a pivotal role in cancer …