Mitochondria autophagy: a potential target for cancer therapy

YH Qiu, TS Zhang, XW Wang, M Wang… - Journal of drug …, 2021 - Taylor & Francis
Mitophagy is a selective form of macroautophagy in which dysfunctional and damaged
mitochondria can be efficiently degraded, removed and recycled through autophagy …

[HTML][HTML] The role of mitochondrial dynamics and mitophagy in carcinogenesis, metastasis and therapy

Y Wang, HH Liu, YT Cao, LL Zhang… - Frontiers in Cell and …, 2020 - frontiersin.org
Mitochondria are key cellular organelles and play vital roles in energy metabolism,
apoptosis regulation and cellular homeostasis. Mitochondrial dynamics refers to the varying …

[HTML][HTML] Autophagy/mitophagy regulated by ubiquitination: a promising pathway in cancer therapeutics

SC Jee, H Cheong - Cancers, 2023 - mdpi.com
Simple Summary Autophagy and mitophagy are important processes in the regulation of
cancer progression. Although autophagy and mitophagy have dual roles in cancer, targeting …

[HTML][HTML] Mitophagy and cancer

AH Chourasia, ML Boland, KF Macleod - Cancer & metabolism, 2015 - Springer
Mitophagy is a selective form of macro-autophagy in which mitochondria are selectively
targeted for degradation in autophagolysosomes. Mitophagy can have the beneficial effect …

The emerging, multifaceted role of mitophagy in cancer and cancer therapeutics

DP Panigrahi, PP Praharaj, CS Bhol… - Seminars in cancer …, 2020 - Elsevier
Mitophagy is an evolutionarily conserved cellular process which selectively eliminates
dysfunctional mitochondria by targeting them to the autophagosome for degradation …

Regulation and function of mitophagy in development and cancer

H Lu, G Li, L Liu, L Feng, X Wang, H Jin - Autophagy, 2013 - Taylor & Francis
Beyond its role in recycling intracellular components nonselectively to sustain survival in
response to metabolic stresses, autophagy can also selectively degrade specific cargoes …

Mitophagy: Link to cancer development and therapy

AV Kulikov, EA Luchkina, V Gogvadze… - … and biophysical research …, 2017 - Elsevier
Mitophagy, the selective degradation of mitochondria via the autophagic pathway, is a vital
mechanism of mitochondrial quality control in cells. Mitophagy is responsible for the removal …

[HTML][HTML] Mitophagy in carcinogenesis and cancer treatment

TV Denisenko, V Gogvadze, B Zhivotovsky - Discover Oncology, 2021 - Springer
In order to maintain a functional mitochondrial network, cells have developed a quality
control mechanism, namely mitophagy. This process can be induced through different …

Mitophagy: A novel perspective for insighting into cancer and cancer treatment

C Song, S Pan, J Zhang, N Li, Q Geng - Cell Proliferation, 2022 - Wiley Online Library
Background Mitophagy refers to the selective self‐elimination of mitochondria under
damaged or certain developmental conditions. As an important regulatory mechanism to …

[HTML][HTML] Mitophagy in cancer: a tale of adaptation

M Vara-Perez, B Felipe-Abrio, P Agostinis - Cells, 2019 - mdpi.com
In the past years, we have learnt that tumors co-evolve with their microenvironment, and that
the active interaction between cancer cells and stromal cells plays a pivotal role in cancer …