Immune reactivity during COVID-19: Implications for treatment

C Napoli, G Benincasa, C Criscuolo, M Faenza… - Immunology letters, 2021 - Elsevier
Clinical symptoms of COVID-19 include fever, cough, and fatigue which may progress to
acute respiratory distress syndrome (ARDS). The main hematological laboratory findings …

T cell activation, highly armed cytotoxic cells and a shift in monocytes CD300 receptors expression is characteristic of patients with severe COVID-19

O Zenarruzabeitia, G Astarloa-Pando, I Terren… - Frontiers in …, 2021 - frontiersin.org
COVID-19 manifests with a wide diversity of clinical phenotypes characterized by
dysfunctional and exaggerated host immune responses. Many results have been described …

Immunological and inflammatory profiles in mild and severe cases of COVID-19

JW Song, C Zhang, X Fan, FP Meng, Z Xu, P Xia… - Nature …, 2020 - nature.com
Abstract COVID-19 is associated with 5.1% mortality. Although the virological,
epidemiological, clinical, and management outcome features of COVID-19 patients have …

[HTML][HTML] Immune Response and COVID-19: A mirror image of Sepsis

E Lopez-Collazo, J Avendano-Ortiz… - … journal of biological …, 2020 - ncbi.nlm.nih.gov
The emergence of SARS-CoV-2 virus and its associated disease COVID-19 have triggered
significant threats to public health, in addition to political and social changes. An important …

Immune response, inflammation, and the clinical spectrum of COVID-19

LF García - Frontiers in immunology, 2020 - frontiersin.org
The current COVID-19 pandemic began in December 2019 in Wuhan (China) and rapidly
extended to become a global sanitary and economic emergency. Its etiological agent is the …

The immune response and immunopathology of COVID-19

E Mortaz, P Tabarsi, M Varahram, G Folkerts… - Frontiers in …, 2020 - frontiersin.org
Coronaviruses were first discovered in the 1960s and are named due to their crown-like
shape. Sometimes, but not often, a coronavirus can infect both animals and humans. An …

Identification of parameters representative of immune dysfunction in patients with severe and fatal COVID-19 infection: a systematic review and meta-analysis

R Qin, L He, Z Yang, N Jia, R Chen, J Xie, W Fu… - Clinical Reviews in …, 2023 - Springer
Abnormal immunological indicators associated with disease severity and mortality in
patients with COVID-19 have been reported in several observational studies. However …

Severe COVID-19: immunosuppression or hyperinflammation?

Y Liu, Y Li, D Xu, J Zhang, Z Peng - Shock, 2021 - journals.lww.com
The ongoing coronavirus disease 2019 (COVID-19) pandemic has swept over the world and
causes thousands of deaths. Although the clinical features of COVID-19 become much …

Humoral immune mechanisms involved in protective and pathological immunity during COVID-19

G Widjaja, AT Jalil, HS Rahman, WK Abdelbasset… - Human Immunology, 2021 - Elsevier
The severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) causing COVID-19 is
associated with excessive inflammation, as a main reason for severe condition and death …

Longitudinal hematologic and immunologic variations associated with the progression of COVID-19 patients in China

R Chen, L Sang, M Jiang, Z Yang, N Jia, W Fu… - Journal of Allergy and …, 2020 - Elsevier
Background Crucial roles of hematologic and immunologic responses in progression of
coronavirus disease 2019 (COVID-19) remain largely unclear. Objective We sought to …