Skeletal muscle deconditioning in breast cancer patients undergoing chemotherapy: current knowledge and insights from other cancers

J Mallard, E Hucteau, TJ Hureau… - Frontiers in Cell and …, 2021 - frontiersin.org
Breast cancer represents the most commonly diagnosed cancer while neoadjuvant and
adjuvant chemotherapies are extensively used in order to reduce tumor development and …

Muscle alterations in the development and progression of cancer-induced muscle atrophy: a review

ME Rosa-Caldwell, DK Fix… - Journal of applied …, 2020 - journals.physiology.org
Cancer cachexia—cancer-associated body weight and muscle loss—is a significant
predictor of mortality and morbidity in cancer patients across a variety of cancer types …

[HTML][HTML] Chemotherapy-induced muscle wasting: an update

D Coletti - European journal of translational myology, 2018 - ncbi.nlm.nih.gov
The majority of cancers are associated to cachexia, a severe form of weight loss mostly
accounted for by skeletal muscle wasting. Cancer patients are often treated with …

The skeletal muscle as an active player against cancer cachexia

F Penna, R Ballarò, M Beltrà, S De Lucia… - Frontiers in …, 2019 - frontiersin.org
The management of cancer patients is frequently complicated by the occurrence of
cachexia. This is a complex syndrome that markedly impacts on quality of life as well as on …

[HTML][HTML] Cancer-associated muscle weakness-From triggers to molecular mechanisms

E Shorter, V Engman, JT Lanner - Molecular Aspects of Medicine, 2024 - Elsevier
Skeletal muscle weakness is a debilitating consequence of many malignancies. Muscle
weakness has a negative impact on both patient wellbeing and outcome in a range of …

Skeletal muscle atrophy and dysfunction in breast cancer patients: role for chemotherapy-derived oxidant stress

BA Guigni, DM Callahan, TW Tourville… - … of Physiology-Cell …, 2018 - journals.physiology.org
How breast cancer and its treatments affect skeletal muscle is not well defined. To address
this question, we assessed skeletal muscle structure and protein expression in 13 women …

Cancer-induced muscle wasting: latest findings in prevention and treatment

Z Aversa, P Costelli… - Therapeutic advances in …, 2017 - journals.sagepub.com
Cancer cachexia is a severe and disabling clinical condition that frequently accompanies
the development of many types of cancer. Muscle wasting is the hallmark of cancer cachexia …

Molecular mechanisms of cancer cachexia‐related loss of skeletal muscle mass: data analysis from preclinical and clinical studies

A Martin, YS Gallot, D Freyssenet - Journal of Cachexia …, 2023 - Wiley Online Library
Cancer cachexia is a systemic hypoanabolic and catabolic syndrome that diminishes the
quality of life of cancer patients, decreases the efficiency of therapeutic strategies and …

Skeletal muscle regeneration in cancer cachexia

M Bossola, E Marzetti, F Rosa… - Clinical and Experimental …, 2016 - Wiley Online Library
Muscle wasting is the most important phenotypic and clinical feature of cancer cachexia, and
the principal cause of impaired physical function, fatigue, and respiratory complications …

Muscle wasting in cancer: opportunities and challenges for exercise in clinical cancer trials

CM Fairman, S Lønbro, TD Cardaci… - JCSM rapid …, 2022 - Wiley Online Library
Background Low muscle in cancer is associated with an increase in treatment‐related
toxicities and is a predictor of cancer‐related and all‐cause mortality. The mechanisms of …