A multimodel regime for evaluating effectiveness of antimicrobial wound care products in microbial biofilms
JJ Stoffel, PL Kohler Riedi… - Wound Repair and …, 2020 - Wiley Online Library
Microbial biofilms have become increasingly recognized as a cause of wound chronicity.
There are several topical antimicrobial wound care products available for use; however …
There are several topical antimicrobial wound care products available for use; however …
Anti-biofilm efficacy of commonly used wound care products in in vitro settings
M Regulski, MF Myntti, GA James - Antibiotics, 2023 - mdpi.com
Considering the prevalence and pathogenicity of biofilms in wounds, this study was
designed to evaluate the anti-biofilm capabilities of eight commercially available wound care …
designed to evaluate the anti-biofilm capabilities of eight commercially available wound care …
Biofilm inhibitory and eradicating activity of wound care products against Staphylococcus aureus and Staphylococcus epidermidis biofilms in an in vitro chronic …
G Brackman, L De Meyer, HJ Nelis… - Journal of applied …, 2013 - academic.oup.com
Aims Although several factors contribute to wound healing, bacterial infections and the
presence of biofilm can significantly affect healing. Despite that this clearly indicates that …
presence of biofilm can significantly affect healing. Despite that this clearly indicates that …
A novel chronic wound biofilm model sustaining coexistence of Pseudomonas aeruginosa and Staphylococcus aureus suitable for testing of antibiofilm effect of …
X Chen, J Lorenzen, Y Xu, M Jonikaite… - Wound Repair and …, 2021 - Wiley Online Library
Chronic wounds are a large burden to patients and healthcare systems. Biofilm infections in
chronic wounds are crucial factors leading to non‐healing of wounds. It is important to study …
chronic wounds are crucial factors leading to non‐healing of wounds. It is important to study …
Modelling antisepsis using defined populations of facultative and anaerobic wound pathogens grown in a basally perfused biofilm model
An in vitro model was developed to assess the effects of topical antimicrobials on
taxonomically defined wound biofilms. Biofilms were exposed over seven days to povidone …
taxonomically defined wound biofilms. Biofilms were exposed over seven days to povidone …
Comparative analysis of biofilm models to determine the efficacy of antimicrobials
EK Stuermer, M Besser, F Brill, M Geffken… - International Journal of …, 2021 - Elsevier
Biofilms are one of the greatest challenges in today's treatment of chronic wounds. While
antimicrobials kill platonic bacteria within seconds, they are rarely able to harm biofilms. In …
antimicrobials kill platonic bacteria within seconds, they are rarely able to harm biofilms. In …
The efficacy of topical agents used in wounds for managing chronic biofilm infections: A systematic review
Objectives Clinicians have increasingly adopted the widespread use of topical agents to
manage chronic wound infections, despite limited data on their effectiveness in vivo. This …
manage chronic wound infections, despite limited data on their effectiveness in vivo. This …
Effects of biofilm treatments on the multi-species Lubbock chronic wound biofilm model
Objective: To evaluate the efficacy of several biofilm effectors in inhibiting biofilm formation
in an in vitro multi-species chronic wound biofilm model. Method: The Lubbock Chronic …
in an in vitro multi-species chronic wound biofilm model. Method: The Lubbock Chronic …
Challenges with wound infection models in drug development
Wound research is an evolving science trying to unfold the complex untold mechanisms
behind the wound healing cascade. In particular, interest is growing regarding the role of …
behind the wound healing cascade. In particular, interest is growing regarding the role of …
In vitro Activity of Antimicrobial Wound Dressings on P. aeruginosa Wound Biofilm
EK Stuermer, I Plattfaut, M Dietrich, F Brill… - Frontiers in …, 2021 - frontiersin.org
The treatment of acute and chronic infected wounds with residing biofilm still poses a major
challenge in medical care. Interactions of antimicrobial dressings with bacterial load, biofilm …
challenge in medical care. Interactions of antimicrobial dressings with bacterial load, biofilm …