Anti-osteoclastogenic effects of isoquinoline alkaloids from the rhizome extract of Sinomenium acutum

JY Lee, KJ Kim, J Kim, SU Choi, SH Kim… - Archives of pharmacal …, 2016 - Springer
A phytochemical investigation for the rhizome extract from Sinomenium acutum
(Menispermaceae) resulted in the isolation of several active principles responsible for the …

Inhibition of osteoclast differentiation by tanshinones from the root ofSalvia miltiorrhiza Bunge

SY Lee, DY Choi, ER Woo - Archives of pharmacal research, 2005 - Springer
We screened natural products to find compounds with anti-osteoporotic potential using a
coculture-based system by which osteoclast differentiation is effectively achieved. We found …

Xylodon flaviporus-Derived Drimane Sesquiterpenoids That Inhibit Osteoclast Differentiation

J Kwon, H Lee, SM Ryu, Y Jang, HC Kwon… - Journal of natural …, 2019 - ACS Publications
The presence of excessive osteoclasts is a major factor in skeletal diseases. The present
study aimed to discover osteoclast differentiation inhibitors from the basidiomycete Xylodon …

Sinoracutine, a novel skeletal alkaloid with cell-protective effects from Sinomenium acutum

GH Bao, XL Wang, XC Tang, P Chiu, GW Qin - Tetrahedron Letters, 2009 - Elsevier
From the stems of Sinomenium acutum, sinoracutine (1) has been isolated, an alkaloid with
a structurally novel skeletal framework, whose structure has been established by spectral …

Taichunins E–T, Isopimarane Diterpenes and a 20-nor-Isopimarane, from Aspergillus taichungensis (IBT 19404): Structures and Inhibitory Effects on RANKL …

AHH El-Desoky, N Inada, Y Maeyama… - Journal of Natural …, 2021 - ACS Publications
Fifteen new isopimarane-type diterpenes, taichunins E–S (1–15), and a new 20-nor-
isopimarane, taichunin T (16), together with four known compounds were isolated from …

New alkaloids sinomacutines A–E, and cephalonine-2-O-β-d-glucopyranoside from rhizomes of Sinomenium acutum

YH Li, HM Li, Y Li, J He, X Deng, LY Peng, LH Gao… - Tetrahedron, 2014 - Elsevier
Phytochemical investigation on the rhizomes of Sinomenium acutum led to the isolation of
new alkaloids sinomacutines A–E (1–5), and cephalonine-2-O-β-d-glucopyranoside (6) …

Enantioselective inhibitory abilities of enantiomers of notoamides against RANKL-induced formation of multinuclear osteoclasts

H Kato, A Kai, T Kawabata, JD Sunderhaus… - Bioorganic & medicinal …, 2017 - Elsevier
The marine-derived Aspergillus protuberus MF297-2 and the terrestrial A. amoenus NRRL
35600 produce enantiomeric prenylated indole alkaloids. Investigation of biological …

Morphinane Alkaloids with Cell Protective Effects from Sinomenium acutum

GH Bao, GW Qin, R Wang, XC Tang - Journal of natural products, 2005 - ACS Publications
One new morphinane alkaloid, sinomenine N-oxide (1), and one new natural occurring
morphinane alkaloid, N-demethylsinomenine (2), together with six known alkaloids, 7, 8 …

Discovery of ingenane and jatrophane diterpenoids from Euphorbia esula as inhibitors of RANKL-induced osteoclastogenesis

S Yuan, Y Zhang, P Hua, H Zhou, J Xu, Q Gu - Fitoterapia, 2020 - Elsevier
Abstract Two new ingenane diterpenoids (1–2), four new jatrophane diterpenoids (3–6), and
seven known analogues (7–13), were isolated from the 95% ethanol extract of Euphorbia …

The Correlation of Salvia miltiorrhiza Extract–Induced Regulation of Osteoclastogenesis with the Amount of Components Tanshinone I, Tanshinone IIA …

HK Kim, ER Woo, HW Lee, HR Park… - …, 2008 - Taylor & Francis
Tanshinone I, tanshinone IIA, cryptotanshinone, and dihydrotanshinone are compounds that
have been isolated from the root of Salvia miltiorrhiza (SM), which is also known as …