Identification and characterization of potential drug targets by subtractive genome analyses of methicillin resistant Staphylococcus aureus

R Uddin, K Saeed - Computational biology and chemistry, 2014 - Elsevier
Methicillin resistant Staphylococcus aureus (MRSA) causes serious infections in humans
and becomes resistant to a number of antibiotics. Due to the emergence of antibiotic …

Metabolic pathway analysis approach: identification of novel therapeutic target against methicillin resistant Staphylococcus aureus

R Uddin, K Saeed, W Khan, SS Azam, A Wadood - Gene, 2015 - Elsevier
Abstract Multiple Drug Resistant (MDR) bacteria are no more inhibited by the front line
antibiotics due to extreme resistance. Methicillin Resistant Staphylococcus aureus (MRSA) …

Identification of putative drug targets in Vancomycin-resistant Staphylococcus aureus (VRSA) using computer aided protein data analysis

MA Hasan, MA Khan, T Sharmin, MHH Mazumder… - Gene, 2016 - Elsevier
Vancomycin-resistant Staphylococcus aureus (VRSA) is a Gram-positive, facultative aerobic
bacterium which is evolved from the extensive exposure of Vancomycin to Methicillin …

[HTML][HTML] Potential therapeutic drug target identification in Community Acquired-Methicillin Resistant Staphylococcus aureus (CA-MRSA) using computational analysis

PK Yadav, G Singh, S Singh, B Gautam, EIF Saad - Bioinformation, 2012 - ncbi.nlm.nih.gov
The emergence of multidrug-resistant strain of community-acquired methicillin resistant
Staphylococcus aureus (CA-MRSA) strain has highlighted the urgent need for the alternative …

Subtractive genome analysis for in silico identification and characterization of novel drug targets in Streptococcus pneumonia strain JJA

A Wadood, A Jamal, M Riaz, A Khan, R Uddin… - Microbial …, 2018 - Elsevier
Streptococcus pneumoniae (pneumococcus) is a Gram-positive bacterium. Humans are the
major target for the pneumococcus. The pneumococcus is a common etiological agent of …

Application of the subtractive genomics and molecular docking analysis for the identification of novel putative drug targets against Salmonella enterica subsp. enterica …

T Hossain, M Kamruzzaman… - BioMed research …, 2017 - Wiley Online Library
The emergence of novel pathogenic strains with increased antibacterial resistance patterns
poses a significant threat to the management of infectious diseases. In this study, we aimed …

Integrated Multi-omics, Virtual Screening and Molecular Docking Analysis of Methicillin-Resistant Staphylococcus aureus USA300 for the Identification of Potential …

S Rahman, AK Das - International journal of peptide research and …, 2021 - Springer
Staphylococcus aureus infection is a leading cause of mortality and morbidity in community,
hospital and live-stock sectors, especially with the widespread emergence of methicillin …

[HTML][HTML] Identification of potential targets in Staphylococcus aureus N315 using computer aided protein data analysis

M Hossain, J Farhana, MT Akbar, A Chakraborty… - …, 2013 - ncbi.nlm.nih.gov
Staphylococcus aureus is a gram positive bacterium, responsible for both community-
acquired and hospital-acquired infection, resulting in a mortality rate of 39%. 43.2 …

Identification of plausible drug targets by investigating the druggable genome of MDR Staphylococcus epidermidis

G Sanober, S Ahmad, SS Azam - Gene Reports, 2017 - Elsevier
Staphyloccocus epidermidis is recently recognized as opportunistic and multidrug resistant
pathogen. In hospital settings, the pathogen is notorious for forming biofilm on indwelling …

[PDF][PDF] In silico identification of drug targets in methicillin/multidrug-resistant Staphylococcusaureus

NL Haag, KK Velk, C Wu - Int. J. Adv. Life Sci, 2012 - Citeseer
This paper reports an extension of an established bioinformatics approach to a new
organism involving more than one strains for comparison. Methicillin/multidrugresistant …