Abstract Background The Cefic Mixtures Industry Ad-hoc Team (MIAT) has investigated how
risks from combined exposures can be effectively identified and managed using concepts …

This paper summarizes current challenges, the potential use of novel scientific
methodologies, and ways forward in the risk assessment and risk management of mixtures …

The number of anthropogenic chemicals, manufactured, by-products, metabolites and
abiotically formed transformation products, counts to hundreds of thousands, at present …

Humans and wildlife can be exposed to an infinite number of different combinations of
chemicals in mixtures via food, consumer products and the environment, which might impact …

This paper reviews regulatory requirements and recent case studies to illustrate how the risk
assessment (RA) of chemical mixtures is conducted, considering both the effects on human …

Humans and wildlife are exposed to an intractably large number of different combinations of
chemicals via food, water, air, consumer products, and other media and sources. This raises …

Focus on risks to human health and the environment from combined exposure to multiple
chemicals (“mixture risk assessment”) has increased in the last couple of decades. There …

Humans and the environment are continuously exposed to a multitude of substances via
different routes of exposure. However, the risk assessment of chemicals for regulatory …

Combined exposures may be categorised as specified combinations or mixtures of
substances, depending on composition and exposure scenario. The major characteristic of a …

Current chemicals regulation operates almost exclusively on a chemical-by-chemical basis,
however there is concern that this approach may not be sufficiently protective if two or more …